SCHEMBL30142951

SCHEMBL30142951

CCOC(=O)Cc1cc(O)cc2oc(-c3ccc(O)cc3)cc(=O)c12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.56
KMT2A Q03164 5/20 0.56
MAPT P10636 5/20 0.56
ALDH1A1 P00352 5/20 0.56
FLT3 P36888 4/20 0.56
CYP3A4 P08684 4/20 0.56
CYP2C9 P11712 4/20 0.56
CYP2C19 P33261 4/20 0.56
MEN1 O00255 4/20 0.56
CYP1A1 P04798 3/20 0.56
CYP1B1 Q16678 3/20 0.56
IP6K2 Q9UHH9 3/20 0.56
GABRP O00591 3/20 0.56
GABRD O14764 3/20 0.56
GABRA1 P14867 3/20 0.56
GABRB1 P18505 3/20 0.56
GABRG2 P18507 3/20 0.56
GABRB3 P28472 3/20 0.56
GABRA5 P31644 3/20 0.56
GABRA3 P34903 3/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL312442 0.81 BACE1 (0.62) KDM4EKMT2AMAPTALDH1A1FLT3
SCHEMBL24183777 0.79 KDM4E (0.69) KDM4EMAPTALDH1A1FLT3CYP3A4
Apigenin SCHEMBL7072654 0.77 CYP1B1 (0.80) KDM4EKMT2AMAPTALDH1A1FLT3
SCHEMBL14749128 0.76 MAPT (0.73) KDM4EKMT2AMAPTALDH1A1FLT3
SCHEMBL312740 0.75 AKR1B1 (0.57) KDM4EKMT2AALDH1A1CYP3A4CYP2C9
SCHEMBL311334 0.75 EGFR (0.46) KDM4EKMT2AMAPTALDH1A1CYP1A1
SCHEMBL311402 0.75 ATM (0.53) KDM4EKMT2AMAPTALDH1A1CYP3A4
Chrysin SCHEMBL28616643 0.75 CYP3A4 (0.68) KDM4EKMT2AMAPTALDH1A1CYP3A4
Apigenin SCHEMBL15475269 0.74 CYP1B1 (0.89) KDM4EKMT2AMAPTALDH1A1FLT3
SCHEMBL31307807 0.73 ALDH1A1 (0.64) KDM4EKMT2AMAPTALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111995605-B Chrysin cinnamate or its derivative and its preparation method 五邑大学 2023-02-17 CN disclosed