SCHEMBL30143777

SCHEMBL30143777

CC1=CC(=O)CC(C)(C)[C@H]1CC[C@@H](C)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O[C@@H]1O[C@H](C(=O)O)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ TYR P14679 6/20 0.40
▸ IGF2R P11717 1/20 0.35
▸ POLB P06746 1/20 0.35
▸ GAA P10253 1/20 0.35
▸ NR1H4 Q96RI1 2/20 0.34
▸ TOP1 P11387 4/20 0.34
▸ MAPT P10636 1/20 0.33
▸ SELE P16581 1/20 0.33
▸ PKM P14618 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30153685 0.87 TYR (0.45) TYRPOLBGAAMAPT
SCHEMBL31053942 0.82 ACHE (0.42) TYRPOLBGAA
SCHEMBL31229542 0.77 TYR (0.44) TYRPOLBGAAMAPT
SCHEMBL30712748 0.72 ACHE (0.46) GAA
SCHEMBL38650628 0.72 ACHE (0.46) GAA
SCHEMBL10014359 0.69 IGF2R (0.50) IGF2R
SCHEMBL14114844 0.67 IGF2R (0.52) TYRIGF2RPOLBNR1H4SELE
SCHEMBL18870467 0.67 IGF2R (0.52) TYRIGF2RPOLBNR1H4SELE
SCHEMBL25566551 0.67 IGF2R (0.50) IGF2RPOLBMAPT
SCHEMBL31253175 0.67 POLB (0.46) TYRPOLBGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12622874-B2 Trans-crocetin compositions and treatment regimens L.E.A.F. HOLDINGS GROUP LLC (US) 2026-05-12 — — US disclosed
US-20260014079-A1 CAROTENOID COMPOSITIONS AND USES THEREOF L E A F HOLDINGS GROUP LLC (US) 2026-01-15 — — US disclosed
US-12523655-B2 Leaf markers for root colonization by arbuscular mycorrhizal fungi in plants MAX PLANCK GESELLSCHAFT (DE) 2026-01-13 — — US disclosed
EP-4667017-A2 CAROTENOID COMPOSITIONS AND USES THEREOF L.E.A.F Holdings Group LLC (US) 2025-12-24 — — EP disclosed
EP-3787607-B1 CAROTENOID COMPOSITIONS AND USES THEREOF L E A F HOLDINGS GROUP LLC (US) 2025-12-10 — — EP disclosed
US-12458597-B2 Carotenoid compositions and uses thereof L.E.A.F. HOLDINGS GROUP LLC (US) 2025-11-04 — — US disclosed
CN-119185280-A Carotenoid composition and use thereof L.E.A.F.控股集团公司 2024-12-27 — — CN disclosed
US-20240350446-A1 CAROTENOID SOLUTIONS AND USES THEREOF L E A F HOLDINGS GROUP LLC (US) 2024-10-24 — — US disclosed
CN-112236134-B Carotenoid composition and use thereof L.E.A.F.控股集团公司 2024-09-13 — — CN disclosed
CN-111787787-B Leaf markers for root colonization of plants by arbuscular mycorrhizal fungi 马克思—普朗克科学促进协会公司 2023-10-03 — — CN disclosed
US-20230277494-A1 TRANS-CROCETIN COMPOSITIONS AND TREATMENT REGIMENS L E A F HOLDINGS GROUP LLC (US) 2023-09-07 — — US disclosed
US-20230270706-A1 TRANS-CROCETIN COMPOSITIONS AND TREATMENT REGIMENS L E A F HOLDINGS GROUP LLC (US) 2023-08-31 — — US disclosed
US-20230210803-A1 TRANS-CROCETIN COMPOSITIONS AND TREATMENT REGIMENS L E A F HOLDINGS GROUP LLC (US) 2023-07-06 — — US disclosed
US-20230134835-A1 METHODS OF SYNTHESIZING CAROTENOIDS L E A F HOLDINGS GROUP LLC (US) 2023-05-04 — — US disclosed
US-20220409565-A1 CAROTENOID COMPOSITIONS AND USES THEREOF L E A F HOLDINGS GROUP LLC (US) 2022-12-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12458597-B2 Carotenoid compositions and uses thereof STARD7, LRAT, HCCS TYR 3000/4885IGF2R 4216/4885POLB 3862/4885
US-12622874-B2 Trans-crocetin compositions and treatment regimens CPT2, SOD1, TFRC TYR 3416/4885IGF2R 3531/4885POLB 4406/4885
US-20230277494-A1 TRANS-CROCETIN COMPOSITIONS AND TREATMENT REGIMENS TTPA, HIF1A, HIF1AN TYR 4411/4885IGF2R 4542/4885POLB 3892/4885
US-20220409565-A1 CAROTENOID COMPOSITIONS AND USES THEREOF STARD7, LRAT, HCCS TYR 3000/4885IGF2R 4216/4885POLB 3862/4885
US-20230210803-A1 TRANS-CROCETIN COMPOSITIONS AND TREATMENT REGIMENS TTPA, HIF1A, HIF1AN TYR 4509/4885IGF2R 4626/4885POLB 3799/4885
US-20230270706-A1 TRANS-CROCETIN COMPOSITIONS AND TREATMENT REGIMENS TTPA, HIF1A, CPT1A TYR 4426/4885IGF2R 4427/4885POLB 4251/4885
US-20260014079-A1 CAROTENOID COMPOSITIONS AND USES THEREOF STARD7, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CPT2 TYR 4052/4885IGF2R 3834/4885POLB 3333/4885
US-20230134835-A1 METHODS OF SYNTHESIZING CAROTENOIDS HCCS, GYS2, GYS1 TYR 2801/4885IGF2R 4465/4885POLB 2025/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback