Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | YAP1 | P46937 | 2/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30148516 | 0.96 | TLR9 (0.45) | TLR9TLR7ABCB1PTPN1MET | |
| SCHEMBL30148495 | 0.85 | MET (0.43) | METAXLMEN1KMT2A | |
| SCHEMBL30148536 | 0.84 | SLC2A1 (0.47) | TLR9TLR7METAXLHDAC8 | |
| SCHEMBL30148507 | 0.84 | YAP1 (0.45) | TLR9TLR7METAXLYAP1 | |
| SCHEMBL30148537 | 0.83 | TLR9 (0.43) | TLR9TLR7METAXLNPC1 | |
| SCHEMBL2475638 | 0.80 | YAP1 (0.46) | TLR9TLR7YAP1SLC2A1 | |
| SCHEMBL31166827 | 0.80 | YAP1 (0.46) | TLR9TLR7YAP1SLC2A1 | |
| SCHEMBL30148527 | 0.76 | MTNR1A (0.38) | METAXLMEN1KMT2A | |
| SCHEMBL17200972 | 0.75 | SIGMAR1 (0.47) | METAXLAPPKMT2A | |
| SCHEMBL15156278 | 0.74 | RORC (0.45) | HDAC1HDAC8HDAC6PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022221774-A1 | ARYL-RING-SUBSTITUTED 3-PHENYLAZETIDINES AND THEIR USE IN METHODS FOR TREATING 5-HT2 RESPONSIVE CONDITIONS | ELEUSIS THERAPEUTICS US, INC. (US) | 2022-10-20 | — | — | WO | disclosed |