Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30148527 | 0.86 | MTNR1A (0.38) | METAXLMTNR1AMTNR1BPDE4B | |
| SCHEMBL30148491 | 0.85 | TLR9 (0.45) | METAXLMEN1KMT2A | |
| SCHEMBL30148516 | 0.85 | TLR9 (0.45) | METAXLMEN1KMT2A | |
| SCHEMBL30148513 | 0.80 | MET (0.41) | METAXLMTNR1AMTNR1BPDE4B | |
| SCHEMBL30148531 | 0.80 | STS (0.50) | METAXLPDE4BROCK2STS | |
| SCHEMBL30148522 | 0.80 | STS (0.50) | METAXLPDE4BROCK2STS | |
| SCHEMBL17200972 | 0.78 | SIGMAR1 (0.47) | METAXLPDE4BPDK2KMT2A | |
| SCHEMBL25308321 | 0.76 | RORC (0.37) | METAXLPDK2ESR2LMNA | |
| SCHEMBL25262953 | 0.76 | RORC (0.37) | METAXLPDK2ESR2LMNA | |
| SCHEMBL15156278 | 0.76 | RORC (0.45) | PDK2ESR2NR1H2RORCGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022221774-A1 | ARYL-RING-SUBSTITUTED 3-PHENYLAZETIDINES AND THEIR USE IN METHODS FOR TREATING 5-HT2 RESPONSIVE CONDITIONS | ELEUSIS THERAPEUTICS US, INC. (US) | 2022-10-20 | — | — | WO | disclosed |