Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 2/20 | 0.50 |
| ▸ | MET | P08581 | 1/20 | 0.47 |
| ▸ | AXL | P30530 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | CTSE | P14091 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30148531 | 1.00 | STS (0.50) | STSMETAXLMEN1KMT2A | |
| SCHEMBL30148536 | 0.85 | SLC2A1 (0.47) | STSMETAXLSLC2A1 | |
| SCHEMBL30148507 | 0.85 | YAP1 (0.45) | METAXLPDE4BSLC2A1 | |
| SCHEMBL19202540 | 0.84 | ALDH1A1 (0.43) | STSMETAXLMEN1KMT2A | |
| SCHEMBL17200972 | 0.83 | SIGMAR1 (0.47) | METAXLKMT2AALDH1A1PDE4B | |
| SCHEMBL16874872 | 0.80 | ALDH1A1 (0.51) | STSALDH1A1GPR119HTTCTSD | |
| SCHEMBL30148495 | 0.80 | MET (0.43) | STSMETAXLMEN1KMT2A | |
| SCHEMBL30148494 | 0.80 | CYP2C19 (0.41) | MEN1KMT2AALDH1A1PDE4BHTT | |
| SCHEMBL31084094 | 0.79 | ALDH1A1 (0.52) | MEN1KMT2AALDH1A1ROCK2 | |
| SCHEMBL29853675 | 0.78 | CYP3A4 (0.40) | STSMETAXLMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022221774-A1 | ARYL-RING-SUBSTITUTED 3-PHENYLAZETIDINES AND THEIR USE IN METHODS FOR TREATING 5-HT2 RESPONSIVE CONDITIONS | ELEUSIS THERAPEUTICS US, INC. (US) | 2022-10-20 | — | — | WO | disclosed |