Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846815 | 0.80 | MEN1 (0.41) | MAPTSMN1; SMN2LMNAHTTMEN1 | |
| SCHEMBL30763475 | 0.78 | SMN1; SMN2 (0.48) | GAAMAPTPOLBSMN1; SMN2LMNA | |
| SCHEMBL9846808 | 0.78 | SMN1; SMN2 (0.48) | GAAMAPTPOLBSMN1; SMN2LMNA | |
| SCHEMBL6974150 | 0.74 | L3MBTL1 (0.45) | GAAMAPTL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL24968848 | 0.73 | HDAC3 (0.52) | GAAPOLBLMNARAB9ANPC1 | |
| SCHEMBL6973377 | 0.73 | LMNA (0.47) | MAPTPOLBL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL28829630 | 0.70 | MAPT (0.49) | GAAMAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL23567966 | 0.70 | AAK1 (0.50) | GAAMAPTPOLBL3MBTL1LMNA | |
| SCHEMBL21900756 | 0.69 | SMN1; SMN2 (0.53) | MAPTPOLBL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL6974180 | 0.69 | ALDH1A1 (0.46) | GAAMAPTSMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |