Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 12/20 | 0.52 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30157636 | 0.87 | P2RX7 (0.56) | P2RX7NPC1RAB9AHDAC1HDAC2 | |
| SCHEMBL30157885 | 0.85 | P2RX7 (0.60) | P2RX7NPC1RAB9ASIGMAR1KMT2A | |
| SCHEMBL30157928 | 0.83 | HDAC1 (0.48) | P2RX7HDAC1HDAC2KMT2A | |
| SCHEMBL30157596 | 0.83 | P2RX7 (0.48) | P2RX7NPC1RAB9AKMT2A | |
| SCHEMBL30158715 | 0.82 | GAA (0.59) | P2RX7HDAC1HDAC2KMT2A | |
| SCHEMBL30157924 | 0.82 | HDAC1 (0.50) | P2RX7SIGMAR1HDAC1HDAC2KMT2A | |
| SCHEMBL30157538 | 0.80 | P2RX7 (0.48) | P2RX7NPC1RAB9ASIGMAR1HDAC1 | |
| SCHEMBL30158065 | 0.79 | SIGMAR1 (0.53) | P2RX7SIGMAR1KMT2A | |
| SCHEMBL30157794 | 0.79 | P2RX7 (0.55) | P2RX7NPC1RAB9ASIGMAR1HDAC1 | |
| SCHEMBL30157930 | 0.79 | P2RX7 (0.46) | P2RX7NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268520-A1 | USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | WO | disclosed |