Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.46 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30157737 | 0.84 | EPHX2 (0.56) | SIGMAR1KMT2AALDH1A1EPHX2 | |
| SCHEMBL30157885 | 0.84 | P2RX7 (0.60) | SIGMAR1P2RX7KMT2AALDH1A1POLB | |
| SCHEMBL30157864 | 0.81 | SIGMAR1 (0.54) | SIGMAR1P2RX7KMT2AALDH1A1KCNH2 | |
| SCHEMBL30157636 | 0.81 | P2RX7 (0.56) | P2RX7KMT2AALDH1A1POLB | |
| SCHEMBL30157407 | 0.79 | BRD4 (0.47) | KMT2A | |
| SCHEMBL30157458 | 0.79 | P2RX7 (0.52) | SIGMAR1P2RX7KMT2A | |
| SCHEMBL30157628 | 0.79 | EPHX2 (0.44) | P2RX7KMT2APOLBEPHX2PTGER3 | |
| SCHEMBL9849508 | 0.78 | SMYD3 (0.75) | SIGMAR1P2RX7KMT2ASMYD3ALDH1A1 | |
| SCHEMBL30157538 | 0.77 | P2RX7 (0.48) | SIGMAR1P2RX7KMT2APTGER4PTGER3 | |
| SCHEMBL1611778 | 0.77 | P2RX7 (0.60) | SIGMAR1P2RX7KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268520-A1 | USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | WO | disclosed |