Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30157636 | 0.86 | P2RX7 (0.56) | P2RX7POLBNPC1RAB9AKMT2A | |
| SCHEMBL30157458 | 0.85 | P2RX7 (0.52) | P2RX7NPC1RAB9AKMT2ASIGMAR1 | |
| SCHEMBL30158065 | 0.84 | SIGMAR1 (0.53) | P2RX7POLBKMT2ASIGMAR1PTGER4 | |
| SCHEMBL30157822 | 0.84 | P2RX7 (0.52) | P2RX7KMT2AMEN1 | |
| SCHEMBL30157538 | 0.82 | P2RX7 (0.48) | P2RX7NPC1RAB9AKMT2ASIGMAR1 | |
| SCHEMBL30157596 | 0.79 | P2RX7 (0.48) | P2RX7NPC1RAB9AKMT2APTGER4 | |
| SCHEMBL1611778 | 0.78 | P2RX7 (0.60) | P2RX7POLBKMT2ASIGMAR1PTGER4 | |
| SCHEMBL30157678 | 0.78 | KMT2A (0.60) | POLBKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL289453 | 0.78 | P2RX7 (0.60) | P2RX7POLBKMT2ASIGMAR1PTGER4 | |
| SCHEMBL24718666 | 0.77 | P2RX7 (0.49) | P2RX7POLBNPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268520-A1 | USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | WO | disclosed |