Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30157885 | 0.82 | P2RX7 (0.60) | P2RX7SIGMAR1PTGER4PTGER3PTGER2 | |
| SCHEMBL30157458 | 0.80 | P2RX7 (0.52) | P2RX7SIGMAR1HDAC1HDAC2KMT2A | |
| SCHEMBL30157636 | 0.79 | P2RX7 (0.56) | P2RX7HDAC1HDAC2KMT2ANPC1 | |
| SCHEMBL30157822 | 0.79 | P2RX7 (0.52) | P2RX7KMT2AMEN1 | |
| SCHEMBL30158065 | 0.77 | SIGMAR1 (0.53) | P2RX7SIGMAR1PTGER4PTGER3PTGER2 | |
| SCHEMBL289453 | 0.76 | P2RX7 (0.60) | P2RX7SIGMAR1PTGER4PTGER3PTGER2 | |
| SCHEMBL1611778 | 0.76 | P2RX7 (0.60) | P2RX7SIGMAR1PTGER4PTGER3PTGER2 | |
| SCHEMBL30157596 | 0.76 | P2RX7 (0.48) | P2RX7PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL30157559 | 0.74 | EPHX2 (0.54) | P2RX7HDAC1HDAC2 | |
| SCHEMBL30157277 | 0.72 | KMT2A (0.48) | P2RX7TACR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268520-A1 | USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | WO | disclosed |