Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
| ▸ | HRH2 | P25021 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19692572 | 0.89 | SIGMAR1 (0.56) | LTA4HSIGMAR1MEN1ALDH1A1KMT2A | |
| SCHEMBL19692548 | 0.88 | ALDH1A1 (0.58) | SIGMAR1MEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL19692561 | 0.80 | SIGMAR1 (0.56) | LTA4HSIGMAR1MEN1ALDH1A1KMT2A | |
| SCHEMBL19692624 | 0.78 | ALDH1A1 (0.57) | SIGMAR1MEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL28285423 | 0.77 | SIGMAR1 (0.64) | LTA4HSIGMAR1HRH3 | |
| SCHEMBL25537466 | 0.77 | SIGMAR1 (0.52) | SIGMAR1MEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL19692518 | 0.76 | ALDH1A1 (0.57) | SIGMAR1MEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL25539990 | 0.74 | KCNA5 (0.53) | SIGMAR1MEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL5709509 | 0.74 | SIGMAR1 (0.54) | LTA4HSIGMAR1MEN1ALDH1A1KMT2A | |
| SCHEMBL3596798 | 0.74 | HTR1A (0.63) | LTA4HSIGMAR1MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11547704-B2 | Chemical compounds | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11547704-B2 | Chemical compounds | ATF4, XBP1, EIF2B5 | LTA4H 2707/4885SIGMAR1 831/4885MEN1 2251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.