Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.49 |
| ▸ | LTA4H | P09960 | 3/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
| ▸ | HRH2 | P25021 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709457 | 0.93 | SIGMAR1 (0.60) | SIGMAR1MEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL5709502 | 0.77 | SIGMAR1 (0.60) | SIGMAR1MEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL28286482 | 0.77 | SIGMAR1 (0.63) | SIGMAR1HRH3LTA4HHRH2HRH1 | |
| SCHEMBL28285417 | 0.76 | SIGMAR1 (0.58) | SIGMAR1MEN1KMT2AHRH3HRH2 | |
| SCHEMBL28632356 | 0.74 | SIGMAR1 (0.56) | SIGMAR1MEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL30165632 | 0.74 | LTA4H (0.54) | SIGMAR1MEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL19692561 | 0.74 | SIGMAR1 (0.56) | SIGMAR1MEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL19692572 | 0.74 | SIGMAR1 (0.56) | SIGMAR1MEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL21418384 | 0.74 | SIGMAR1 (0.70) | SIGMAR1HRH3LTA4H | |
| SCHEMBL3589202 | 0.74 | FAAH (0.54) | SIGMAR1MEN1ALDH1A1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720550-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | Sanofi-Aventis (FR) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005089759-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI-AVENTIS (FR) | 2005-09-29 | — | — | WO | disclosed |