Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.75 |
| ▸ | HTR2A | P28223 | 4/20 | 0.75 |
| ▸ | HRH1 | P35367 | 4/20 | 0.75 |
| ▸ | HTR2C | P28335 | 4/20 | 0.75 |
| ▸ | HTR1A | P08908 | 3/20 | 0.75 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.75 |
| ▸ | HRH2 | P25021 | 3/20 | 0.75 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.75 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.75 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.75 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.75 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.75 |
| ▸ | DRD1 | P21728 | 3/20 | 0.75 |
| ▸ | DRD4 | P21917 | 3/20 | 0.75 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.75 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.75 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.75 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL142222 | 1.00 | DRD2 (0.75) | DRD2HTR2AHRH1HTR2CHTR1A | |
| SCHEMBL2738764 | 0.93 | DRD2 (0.74) | DRD2HTR2AHRH1HTR2CHTR1A | |
| SCHEMBL3412948 | 0.86 | HRH1 (0.71) | DRD2HTR2AHRH1HTR2CHTR1A | |
| SCHEMBL11882173 | 0.86 | HRH4 (0.75) | DRD2HTR2AHRH1HTR2CHTR1A | |
| Amoxapine SCHEMBL29370074 | 0.86 | DRD2 (1.00) | DRD2HTR2AHRH1HTR2CHTR1A | |
| Amoxapine SCHEMBL29482386 | 0.86 | DRD2 (1.00) | DRD2HTR2AHRH1HTR2CHTR1A | |
| Amoxapine SCHEMBL33950 | 0.86 | DRD2 (1.00) | DRD2HTR2AHRH1HTR2CHTR1A | |
| Amoxapine SCHEMBL29354942 | 0.86 | DRD2 (1.00) | DRD2HTR2AHRH1HTR2CHTR1A | |
| Amoxapine SCHEMBL5498936 | 0.86 | DRD2 (1.00) | DRD2HTR2AHRH1HTR2CHTR1A | |
| Amoxapine SCHEMBL29180215 | 0.85 | DRD2 (0.98) | DRD2HTR2AHRH1HTR2CHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4437342-A1 | LRRC4 FAMILY MIMIC MOLECULES AND DIAGNOSTIC USES THEREOF | Neuracle Science Co., Ltd. (KR) | 2024-10-02 | — | — | EP | disclosed |
| EP-4367090-A1 | INHIBITORS AND USES THEREOF | Neuracle Science Co., Ltd. (KR) | 2024-05-15 | — | — | EP | disclosed |
| EP-4367128-A1 | POLYPEPTIDE INHIBITORS AND USES THEREOF | Neuracle Science Co., Ltd. (KR) | 2024-05-15 | — | — | EP | disclosed |
| WO-2023095001-A1 | LRRC4 FAMILY MIMIC MOLECULES AND DIAGNOSTIC USES THEREOF | NEURACLE SCIENCE CO., LTD. (KR) | 2023-06-01 | — | — | WO | disclosed |
| WO-2023281476-A1 | INHIBITORS AND USES THEREOF | NEURACLE SCIENCE CO., LTD. (KR) | 2023-01-12 | — | — | WO | disclosed |
| WO-2023281475-A1 | POLYPEPTIDE INHIBITORS AND USES THEREOF | NEURACLE SCIENCE CO., LTD. (KR) | 2023-01-12 | — | — | WO | disclosed |