Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EEF2K | O00418 | 7/20 | 0.35 |
| ▸ | CD38 | P28907 | 2/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NNMT | P40261 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30174264 | 0.80 | NNMT (0.39) | KDM4EKMT2ANNMT | |
| SCHEMBL28966254 | 0.80 | NEK2 (0.43) | CHEK1CHEK2KDM4E | |
| SCHEMBL30174299 | 0.79 | KDM4E (0.36) | KDM4EKMT2ASIRT3TDP1NNMT | |
| SCHEMBL30174213 | 0.75 | CHEK2 (0.40) | CHEK2KDM4EKMT2AEEF2KNNMT | |
| SCHEMBL30174294 | 0.75 | CHEK2 (0.40) | CHEK2KMT2AEEF2KSIRT3TDP1 | |
| SCHEMBL30174265 | 0.74 | CYP2A6 (0.43) | KMT2AEEF2KSIRT3TDP1NNMT | |
| SCHEMBL30174194 | 0.72 | CHEK2 (0.45) | CHEK1CHEK2KDM4E | |
| SCHEMBL29812284 | 0.72 | LMNA (0.44) | KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL29812079 | 0.71 | LMNA (0.44) | KMT2ATDP1 | |
| SCHEMBL30174202 | 0.70 | TGFBR1 (0.38) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605478-A | Compounds and methods of use | 埃克塞里艾克西斯公司（US） | 2023-01-13 | — | — | CN | disclosed |