Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 3/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | GABRE | P78334 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30174243 | 0.80 | CHEK1 (0.39) | NNMTKDM4EKMT2A | |
| SCHEMBL28966254 | 0.78 | NEK2 (0.43) | SYKKDM4EGRIN2BGRIN1 | |
| SCHEMBL30174299 | 0.77 | KDM4E (0.36) | NNMTSYKKDM4EKMT2AHPGDS | |
| SCHEMBL30174189 | 0.76 | HPGDS (0.34) | KDM4EHPGDSSLC6A7DAO | |
| SCHEMBL30174261 | 0.75 | HPGDS (0.36) | KDM4EKMT2APARP1HPGDSSLC6A7 | |
| SCHEMBL30174194 | 0.73 | CHEK2 (0.45) | KDM4EGRIN2BGRIN1 | |
| SCHEMBL30174294 | 0.73 | CHEK2 (0.40) | NNMTSYKKMT2A | |
| SCHEMBL30174213 | 0.73 | CHEK2 (0.40) | NNMTSYKKDM4EKMT2APARP1 | |
| SCHEMBL30174265 | 0.72 | CYP2A6 (0.43) | NNMTKMT2AHPGDS | |
| SCHEMBL29812284 | 0.70 | LMNA (0.44) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605478-A | Compounds and methods of use | 埃克塞里艾克西斯公司（US） | 2023-01-13 | — | — | CN | disclosed |