Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.33 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | GCK | P35557 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30174200 | 0.79 | KDM4E (0.51) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL30174207 | 0.78 | KMT2A (0.40) | HPGDSDAOKDM4EALDH1A1MAPT | |
| SCHEMBL30174189 | 0.76 | HPGDS (0.34) | HPGDSSLC6A7PKMYT1DAOKDM4E | |
| SCHEMBL30174264 | 0.75 | NNMT (0.39) | HPGDSGRIN2BGRIN1SLC6A7DAO | |
| SCHEMBL30174327 | 0.73 | CYP2A6 (0.44) | HPGDSPKMYT1 | |
| SCHEMBL30174277 | 0.73 | CHEK2 (0.46) | KDM4EALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL30174280 | 0.71 | IKBKB (0.43) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL29812074 | 0.70 | SQOR (0.43) | GSK3B | |
| SCHEMBL30174231 | 0.69 | CYP3A4 (0.50) | — | |
| SCHEMBL30174307 | 0.69 | IKBKB (0.45) | KDM4EALDH1A1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605478-A | Compounds and methods of use | 埃克塞里艾克西斯公司（US） | 2023-01-13 | — | — | CN | disclosed |