Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 4/20 | 0.33 |
| ▸ | HRH1 | P35367 | 4/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30185551 | 0.77 | TSHR (0.32) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL29099535 | 0.77 | HRH2 (0.36) | MPLPRMT6MAPTSMN1; SMN2HRH2 | |
| SCHEMBL30185591 | 0.77 | HRH2 (0.36) | MPLPRMT6MAPTSMN1; SMN2HRH2 | |
| SCHEMBL31544002 | 0.69 | MEN1 (0.40) | MPLMEN1KMT2ANPC1RAB9A | |
| SCHEMBL28357048 | 0.66 | TGFBR1 (0.57) | MEN1KMT2ANPC1RAB9AGAA | |
| SCHEMBL330359 | 0.65 | BRD4 (0.51) | ALDH1A1SMN1; SMN2HRH2HRH1HRH4 | |
| SCHEMBL12555393 | 0.65 | ALDH1A1 (0.49) | MEN1KMT2ANPC1RAB9AGAA | |
| SCHEMBL28357002 | 0.65 | HSD17B10 (0.49) | MEN1KMT2ANPC1RAB9AGAA | |
| SCHEMBL149617 | 0.63 | HSD11B1 (0.36) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL31544001 | 0.62 | PRMT6 (0.37) | MPLMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611883-B | PI3K alpha inhibitor with double-ring structure, and preparation method and application thereof | 生物岛实验室 | 2025-03-28 | — | — | CN | disclosed |
| CN-115611883-A | PI3K alpha inhibitor with bicyclic structure and preparation method and application thereof | 生物岛实验室 | 2023-01-17 | — | — | CN | disclosed |