Avicularin

Avicularin

SCHEMBL30185786

O=c1c(O[C@H]2O[C@@H](CO)[C@H](O)[C@H]2O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 4/20 1.00
L3MBTL1 Q9Y468 2/20 1.00
KDM4E B2RXH2 5/20 0.98
P4HB P07237 5/20 0.98
EPHX2 P34913 5/20 0.98
GAA P10253 4/20 0.98
POLB P06746 3/20 0.98
MAPT P10636 3/20 0.98
CA12 O43570 3/20 0.98
CA2 P00918 3/20 0.98
CA4 P22748 3/20 0.98
CA7 P43166 3/20 0.98
ALPL P05186 2/20 0.98
ALPI P09923 2/20 0.98
ADRA2C P18825 1/20 0.98
NOX4 Q9NPH5 1/20 0.98
KDM1A O60341 1/20 0.98
SLCO2B1 O94956 1/20 0.98
HMGB1 P09429 1/20 0.98
PKM P14618 1/20 0.98

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Avicularin SCHEMBL1252098 1.00 AKR1B1 (1.00) AKR1B1L3MBTL1KDM4EP4HBEPHX2
Avicularin SCHEMBL151758 1.00 AKR1B1 (1.00) AKR1B1L3MBTL1KDM4EP4HBEPHX2
Avicularin SCHEMBL30637540 1.00 AKR1B1 (1.00) AKR1B1L3MBTL1KDM4EP4HBEPHX2
Avicularin SCHEMBL29505880 1.00 AKR1B1 (1.00) AKR1B1L3MBTL1KDM4EP4HBEPHX2
Avicularin SCHEMBL119816 1.00 AKR1B1 (1.00) AKR1B1L3MBTL1KDM4EP4HBEPHX2
Avicularin SCHEMBL13182845 1.00 AKR1B1 (1.00) AKR1B1L3MBTL1KDM4EP4HBEPHX2
Avicularin SCHEMBL25174412 1.00 AKR1B1 (1.00) AKR1B1L3MBTL1KDM4EP4HBEPHX2
Avicularin SCHEMBL1626867 1.00 AKR1B1 (1.00) AKR1B1L3MBTL1KDM4EP4HBEPHX2
Avicularin SCHEMBL181203 1.00 AKR1B1 (1.00) AKR1B1L3MBTL1KDM4EP4HBEPHX2
Isoquercetin SCHEMBL12710506 0.99 P4HB (1.00) AKR1B1L3MBTL1KDM4EP4HBEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023219526-A1 MULTITARGET ANTIVIRAL DIETARY SUPPLEMENT PROKIN MILAN (RS) 2023-11-16 WO claimed
WO-2024196032-A1 COMPOSITION FOR PREVENTING OR TREATING VARICELLA-ZOSTER VIRUS INFECTION COMPRISING ELAEOCARPUS SYLVESTRIS-DERIVED INGREDIENT AND GERANIIN BLOOD METABOLITE AS ACTIVE INGREDIENTS 주식회사 제넨셀 2024-09-26 WO disclosed
EP-4162943-B1 COMPOSITION FOR THE TREATMENT AND THE PREVENTION OF PATHOLOGIES OF THE PROSTATE AND URINARY TRACT ANVEST GROUP S R L (IT) 2024-04-10 EP disclosed
WO-2023219526-A1 MULTITARGET ANTIVIRAL DIETARY SUPPLEMENT PROKIN MILAN (RS) 2023-11-16 WO disclosed
EP-4162943-A1 COMPOSITION FOR THE TREATMENT AND THE PREVENTION OF PATHOLOGIES OF THE PROSTATE AND URINARY TRACT Anvest Group S.r.l. (IT) 2023-04-12 EP disclosed
CN-115605254-A Balloon catheter with precise drug elution capability 巴德股份有限公司(US) 2023-01-13 CN disclosed