Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 4/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.98 |
| ▸ | P4HB | P07237 | 5/20 | 0.98 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.98 |
| ▸ | GAA | P10253 | 4/20 | 0.98 |
| ▸ | POLB | P06746 | 3/20 | 0.98 |
| ▸ | MAPT | P10636 | 3/20 | 0.98 |
| ▸ | CA12 | O43570 | 3/20 | 0.98 |
| ▸ | CA2 | P00918 | 3/20 | 0.98 |
| ▸ | CA4 | P22748 | 3/20 | 0.98 |
| ▸ | CA7 | P43166 | 3/20 | 0.98 |
| ▸ | ALPL | P05186 | 2/20 | 0.98 |
| ▸ | ALPI | P09923 | 2/20 | 0.98 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.98 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.98 |
| ▸ | KDM1A | O60341 | 1/20 | 0.98 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.98 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.98 |
| ▸ | PKM | P14618 | 1/20 | 0.98 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Avicularin SCHEMBL1252098 | 1.00 | AKR1B1 (1.00) | AKR1B1L3MBTL1KDM4EP4HBEPHX2 | |
| Avicularin SCHEMBL151758 | 1.00 | AKR1B1 (1.00) | AKR1B1L3MBTL1KDM4EP4HBEPHX2 | |
| Avicularin SCHEMBL30637540 | 1.00 | AKR1B1 (1.00) | AKR1B1L3MBTL1KDM4EP4HBEPHX2 | |
| Avicularin SCHEMBL29505880 | 1.00 | AKR1B1 (1.00) | AKR1B1L3MBTL1KDM4EP4HBEPHX2 | |
| Avicularin SCHEMBL119816 | 1.00 | AKR1B1 (1.00) | AKR1B1L3MBTL1KDM4EP4HBEPHX2 | |
| Avicularin SCHEMBL13182845 | 1.00 | AKR1B1 (1.00) | AKR1B1L3MBTL1KDM4EP4HBEPHX2 | |
| Avicularin SCHEMBL25174412 | 1.00 | AKR1B1 (1.00) | AKR1B1L3MBTL1KDM4EP4HBEPHX2 | |
| Avicularin SCHEMBL30185786 | 1.00 | AKR1B1 (1.00) | AKR1B1L3MBTL1KDM4EP4HBEPHX2 | |
| Avicularin SCHEMBL181203 | 1.00 | AKR1B1 (1.00) | AKR1B1L3MBTL1KDM4EP4HBEPHX2 | |
| Isoquercetin SCHEMBL12710506 | 0.99 | P4HB (1.00) | AKR1B1L3MBTL1KDM4EP4HBEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12233101-B2 | Compositions and methods useful in treatment of lower urinary tract symptoms, benign prostatic hyperplasia, erectile dysfunction, and other diseases or symptoms | NATUREX INC. (US) | 2025-02-25 | — | — | US | claimed |
| US-12163004-B2 | Polymer composites | WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) | 2024-12-10 | — | — | US | claimed |
| CN-116077548-A | Compositions and methods for treating lower urinary tract symptoms, benign prostatic hypertrophy, and erectile dysfunction | 奇华顿股份有限公司 | 2023-05-09 | — | — | CN | claimed |
| US-20220370449-A1 | COMBINED PHARMACEUTICAL COMPOSITION | GIDD COMMERCIAL USA, INC. | 2022-11-24 | — | — | US | claimed |
| US-11406636-B2 | Combined pharmaceutical composition | GIDD COMMERCIAL USA, INC. (US) | 2022-08-09 | — | — | US | claimed |
| US-20220175863-A1 | COMPOSITIONS AND METHODS USEFUL IN TREATMENT OF LOWER URINARY TRACT SYMPTOMS, BENIGN PROSTATIC HYPERPLASIA, ERECTILE DYSFUNCTION, AND OTHER DISEASES OR SYMPTOMS | NATUREX INC. | 2022-06-09 | — | — | US | claimed |
| CN-114318549-A | Monocrystalline silicon texturing additive for weak rough polishing process and use method | 嘉兴市小辰光伏科技有限公司 | 2022-04-12 | — | — | CN | claimed |
| US-11291703-B2 | Compositions and methods useful in treatment of lower urinary tract symptoms, benign prostatic hyperplasia, erectile dysfunction and other diseases or symptoms | NATUREX INC. (US) | 2022-04-05 | — | — | US | claimed |
| US-20220000959-A1 | APPLE PEEL POLYPHENOL EXTRACT FOR THE PREVENTION AND THE TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE | LEAHY ORCHARDS INC. (CA) | 2022-01-06 | — | — | US | claimed |
| EP-3880223-A1 | APPLE PEEL POLYPHENOL EXTRACT FOR THE PREVENTION AND THE TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE | Leahy Orchards Inc. (CA) | 2021-09-22 | — | — | EP | claimed |
| US-20190183892-A1 | COMBINED PHARMACEUTICAL COMPOSITION | GIDD COMMERCIAL USA, INC. | 2019-06-20 | — | — | US | claimed |
| US-20180256663-A1 | COMPOSITIONS AND METHODS USEFUL IN TREATMENT OF LOWER URINARY TRACT SYMPTOMS, BENIGN PROSTATIC HYPERPLASIA, ERECTILE DYSFUNCTION AND OTHER DISEASES OR SYMPTOMS | NATUREX INC. | 2018-09-13 | — | — | US | claimed |
| US-20160324911-A1 | COMPOSITIONS AND METHODS USEFUL IN TREATMENT OF LOWER URINARY TRACT SYMPTOMS, BENIGN PROSTATIC HYPERPLASIA, ERECTILE DYSFUNCTION | Naturex-DBS, LLC | 2016-11-10 | — | — | US | claimed |
| EP-3068414-A1 | COMPOSITIONS AND METHODS USEFUL IN TREATMENT OF LOWER URINARY TRACT SYSPTOMS, BENIGN PROSTATIC HYPERPLASIA, ERECTILE DYSFUNCTION | Naturex-DBS LLC (US) | 2016-09-21 | — | — | EP | claimed |
| WO-2016046375-A1 | THEOBROMA CACAO EXTRACT FOR USE IN THE TREATMENT OR PREVENTION OF RECEPTOR TYROSINE KINASES RELATED DISORDERS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2016-03-31 | — | — | WO | claimed |
| EP-2976061-A1 | COMBINATIONS OF N-ACETYL CYSTEINE DERIVATIVES AND CRANBERRY POLYPHENOLS IN COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING PERIODONTAL DISEASES AND PERI-IMPLATITIS | Dentalmed Pharm Holding Ltd. (BE) | 2016-01-27 | — | — | EP | claimed |
| WO-2015070203-A1 | COMPOSITIONS AND METHODS USEFUL IN TREATMENT OF LOWER URINARY TRACT SYSPTOMS, BENIGN PROSTATIC HYPERPLASIA, ERECTILE DYSFUNCTION | NATUREX-DBS LLC (US) | 2015-05-14 | — | — | WO | claimed |
| WO-2014147613-A1 | COMBINATIONS OF N-ACETYL CYSTEINE DERIVATIVES AND CRANBERRY POLYPHENOLS IN COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING PERIODONTAL DISEASES AND PERI-IMPLATITIS | DENTALMED PHARM HOLDING LTD. (BE) | 2014-09-25 | — | — | WO | claimed |
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | claimed |
| EP-0507035-A1 | Meadowsweet extracts, preparation and use thereof | SYNTHELABO (FR) | 1992-10-07 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220000959-A1 | APPLE PEEL POLYPHENOL EXTRACT FOR THE PREVENTION AND THE TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE | GOT2, FABP2, LIPC | AKR1B1 697/4885L3MBTL1 2197/4885KDM4E 1785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.