Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 4/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.98 |
| ▸ | P4HB | P07237 | 5/20 | 0.98 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.98 |
| ▸ | GAA | P10253 | 4/20 | 0.98 |
| ▸ | POLB | P06746 | 3/20 | 0.98 |
| ▸ | MAPT | P10636 | 3/20 | 0.98 |
| ▸ | CA12 | O43570 | 3/20 | 0.98 |
| ▸ | CA2 | P00918 | 3/20 | 0.98 |
| ▸ | CA4 | P22748 | 3/20 | 0.98 |
| ▸ | CA7 | P43166 | 3/20 | 0.98 |
| ▸ | ALPL | P05186 | 2/20 | 0.98 |
| ▸ | ALPI | P09923 | 2/20 | 0.98 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.98 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.98 |
| ▸ | KDM1A | O60341 | 1/20 | 0.98 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.98 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.98 |
| ▸ | PKM | P14618 | 1/20 | 0.98 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Avicularin SCHEMBL151758 | 1.00 | AKR1B1 (1.00) | AKR1B1L3MBTL1KDM4EP4HBEPHX2 | |
| Avicularin SCHEMBL30637540 | 1.00 | AKR1B1 (1.00) | AKR1B1L3MBTL1KDM4EP4HBEPHX2 | |
| Avicularin SCHEMBL29505880 | 1.00 | AKR1B1 (1.00) | AKR1B1L3MBTL1KDM4EP4HBEPHX2 | |
| Avicularin SCHEMBL119816 | 1.00 | AKR1B1 (1.00) | AKR1B1L3MBTL1KDM4EP4HBEPHX2 | |
| Avicularin SCHEMBL13182845 | 1.00 | AKR1B1 (1.00) | AKR1B1L3MBTL1KDM4EP4HBEPHX2 | |
| Avicularin SCHEMBL25174412 | 1.00 | AKR1B1 (1.00) | AKR1B1L3MBTL1KDM4EP4HBEPHX2 | |
| Avicularin SCHEMBL1626867 | 1.00 | AKR1B1 (1.00) | AKR1B1L3MBTL1KDM4EP4HBEPHX2 | |
| Avicularin SCHEMBL30185786 | 1.00 | AKR1B1 (1.00) | AKR1B1L3MBTL1KDM4EP4HBEPHX2 | |
| Avicularin SCHEMBL181203 | 1.00 | AKR1B1 (1.00) | AKR1B1L3MBTL1KDM4EP4HBEPHX2 | |
| Isoquercetin SCHEMBL12710506 | 0.99 | P4HB (1.00) | AKR1B1L3MBTL1KDM4EP4HBEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2976061-B1 | COMBINATIONS OF N-ACETYL CYSTEINE DERIVATIVES AND CRANBERRY POLYPHENOLS IN COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING PERIODONTAL DISEASES AND PERI-IMPLATITIS | DENTALMED PHARM HOLDING LTD (BE) | 2019-10-16 | — | — | EP | claimed |
| US-20110034427-A1 | Anti-aging properties of quercetin, 18alpha-glycyrrhetinic acid and hederagenin and their derivatives | KORRES S.A. NATURAL PRODUCTS (GR) | 2011-02-10 | — | — | US | claimed |
| CN-111467380-B | Penthorum chinense pursh extract microcapsule and preparation method thereof | 四川大学 | 2021-06-15 | — | — | CN | disclosed |
| CN-111467380-A | Penthorum chinense pursh extract microcapsule and preparation method thereof | 四川大学 | 2020-07-31 | — | — | CN | disclosed |
| WO-2014157812-A1 | COMPOSITION FOR HELPING WITH JOINT HEALTH, OR PREVENTING, REMEDYING, OR TREATING RHEUMATOID ARTHRITIS AND OSTEOARTHRITIS | 유한회사한풍제약 (KR) | 2014-10-02 | — | — | WO | disclosed |
| US-20110034427-A1 | Anti-aging properties of quercetin, 18alpha-glycyrrhetinic acid and hederagenin and their derivatives | KORRES S.A. NATURAL PRODUCTS (GR) | 2011-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034427-A1 | Anti-aging properties of quercetin, 18alpha-glycyrrhetinic acid and hederagenin and their derivatives | GLA, AGER, CUTA | AKR1B1 1541/4885L3MBTL1 4645/4885KDM4E 2688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.