SCHEMBL30195176

SCHEMBL30195176

CC(C)(C)c1nc2ccccc2n1Cc1ccc(Br)cc1

nearest known ligand 0.68

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GALR3 O60755 2/20 0.68
NR2F2 P24468 2/20 0.68
MEN1 O00255 2/20 0.60
KMT2A Q03164 2/20 0.60
NPSR1 Q6W5P4 2/20 0.60
RAB9A P51151 2/20 0.60
LMNA P02545 1/20 0.60
TSHR P16473 1/20 0.60
TBXA2R P21731 1/20 0.57
ALOX5AP P20292 1/20 0.53
TP53 P04637 3/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
HPGD P15428 1/20 0.52
POLB P06746 1/20 0.51
TNF P01375 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7756931 0.88 TNF (0.64) MEN1KMT2ALMNATSHRTP53
SCHEMBL7761087 0.87 GALR3 (0.67) GALR3NR2F2MEN1KMT2ANPSR1
SCHEMBL7761652 0.87 TP53 (0.63) GALR3NR2F2MEN1KMT2ANPSR1
SCHEMBL6244545 0.81 AGTR1 (0.65) MEN1KMT2ALMNATBXA2RTP53
SCHEMBL12771519 0.81 GALR3 (1.00) GALR3NR2F2MEN1KMT2ANPSR1
SCHEMBL7259937 0.78 RAB9A (0.74) GALR3NR2F2MEN1KMT2ANPSR1
SCHEMBL7756940 0.77 ALOX5AP (0.64) MEN1KMT2ANPSR1LMNATSHR
SCHEMBL7762123 0.77 HTT (0.59) MEN1KMT2ANPSR1RAB9ALMNA
SCHEMBL13941731 0.76 NOD1 (0.63) GALR3NR2F2MEN1KMT2ANPSR1
SCHEMBL12771528 0.75 LMNA (0.69) GALR3NR2F2MEN1KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12441718-B2 Selective angiotensin II compounds VICORE PHARMA AB (SE) 2025-10-14 US disclosed
US-20250101010-A1 SELECTIVE ANGIOTENSIN II COMPOUNDS VICORE PHARMA AB (SE) 2025-03-27 US disclosed
US-20240262813-A1 NEW SELECTIVE ANGIOTENSIN II COMPOUNDS VICORE PHARMA AB (SE) 2024-08-08 US disclosed
CN-117916229-A Novel selective angiotensin II compounds 维科尔药物公司 2024-04-19 CN disclosed
WO-2023281271-A1 NEW SELECTIVE ANGIOTENSIN II COMPOUNDS VICORE PHARMA AB (SE) 2023-01-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240262813-A1 NEW SELECTIVE ANGIOTENSIN II COMPOUNDS AGTR1, AGTR2, REN GALR3 116/4885NR2F2 2410/4885MEN1 999/4885
US-20250101010-A1 SELECTIVE ANGIOTENSIN II COMPOUNDS AGTR1, AGTR2, REN GALR3 99/4885NR2F2 2406/4885MEN1 588/4885
US-12441718-B2 Selective angiotensin II compounds AGTR1, AGTR2, REN GALR3 99/4885NR2F2 2406/4885MEN1 588/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.