SCHEMBL30195276

SCHEMBL30195276

c1ccc(SSC2CCCCC2)nc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EHMT2 Q96KQ7 1/20 0.55
EHMT1 Q9H9B1 1/20 0.55
APOBEC3G Q9HC16 1/20 0.55
TXN P10599 4/20 0.47
ALDH1A1 P00352 5/20 0.42
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42
TSHR P16473 1/20 0.42
HTT P42858 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
CYP1A2 P05177 1/20 0.40
GRM5 P41594 1/20 0.40
KDM4E B2RXH2 2/20 0.39
GAA P10253 1/20 0.39
CRBN Q96SW2 2/20 0.38
DDB1 Q16531 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.36
MAPT P10636 2/20 0.36
NPC1 O15118 1/20 0.35
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16710894 1.00 EHMT2 (0.55) EHMT2EHMT1APOBEC3GTXNALDH1A1
SCHEMBL29601254 1.00 EHMT2 (0.55) EHMT2EHMT1APOBEC3GTXNALDH1A1
SCHEMBL22882906 1.00 EHMT2 (0.55) EHMT2EHMT1APOBEC3GTXNALDH1A1
SCHEMBL30448686 0.98 EHMT2 (0.57) EHMT2EHMT1APOBEC3GTXNALDH1A1
SCHEMBL22882815 0.98 EHMT2 (0.57) EHMT2EHMT1APOBEC3GTXNALDH1A1
SCHEMBL22893342 0.83 EHMT2 (0.52) EHMT2EHMT1APOBEC3GTXNALDH1A1
SCHEMBL22882827 0.83 EHMT2 (0.52) EHMT2EHMT1APOBEC3GTXNALDH1A1
SCHEMBL22882826 0.83 EHMT2 (0.52) EHMT2EHMT1APOBEC3GTXNALDH1A1
SCHEMBL12949631 0.81 EHMT2 (0.48) EHMT2EHMT1APOBEC3GALDH1A1KMT2A
SCHEMBL15271760 0.81 EHMT2 (0.48) EHMT2EHMT1APOBEC3GALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250361260-A1 NUCLEOTIDE ANALOGUES SINGULAR GENOMICS SYSTEMS INC (US) 2025-11-27 US disclosed
US-12215122-B2 Nucleotide analogues Singular Genomics Systems, Inc. (US) 2025-02-04 US disclosed
US-20240400602-A1 NUCLEOTIDE ANALOGUES FIRST-CITIZENS BANK & TRUST COMPANY 2024-12-05 US disclosed
US-12145960-B2 Nucleotide analogues Singular Genomics Systems, Inc. (US) 2024-11-19 US disclosed
US-20240316036-A1 DISULFIDE CONTAINING THERAPEUTICS AND DIAGNOSTICS FIRST-CITIZENS BANK & TRUST COMPANY 2024-09-26 US disclosed
US-20240269156-A1 DISULFIDE CONTAINING THERAPEUTICS FIRST-CITIZENS BANK & TRUST COMPANY 2024-08-15 US disclosed
US-20240174709-A1 NUCLEOTIDE ANALOGUES FIRST-CITIZENS BANK & TRUST COMPANY 2024-05-30 US disclosed
US-11958877-B2 Nucleotide analogues Singular Genomics Systems, Inc. (US) 2024-04-16 US disclosed
US-11878993-B2 Nucleotide analogues Singular Genomics Systems, Inc. (US) 2024-01-23 US disclosed
US-20230257414-A1 NUCLEOTIDE ANALOGUES FIRST-CITIZENS BANK & TRUST COMPANY 2023-08-17 US disclosed
US-20230203083-A1 NUCLEOTIDE ANALOGUES FIRST-CITIZENS BANK & TRUST COMPANY 2023-06-29 US disclosed
US-20230028359-A1 NUCLEOTIDE ANALOGUES FIRST-CITIZENS BANK & TRUST COMPANY 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12215122-B2 Nucleotide analogues NUDT1, POLN, TYMP EHMT2 2494/4885EHMT1 2450/4885APOBEC3G 226/4885
US-20240400602-A1 NUCLEOTIDE ANALOGUES ADAR, NUDT1, NSUN2 EHMT2 938/4885EHMT1 923/4885APOBEC3G 236/4885
US-20240316036-A1 DISULFIDE CONTAINING THERAPEUTICS AND DIAGNOSTICS GPX1, GPX4, PDIA4 EHMT2 2946/4885EHMT1 3031/4885APOBEC3G 4047/4885
US-20250361260-A1 NUCLEOTIDE ANALOGUES ADAR, NUDT1, NSUN2 EHMT2 938/4885EHMT1 923/4885APOBEC3G 236/4885
US-20230257414-A1 NUCLEOTIDE ANALOGUES ITPA, POLB, NUDT1 EHMT2 2878/4885EHMT1 3389/4885APOBEC3G 437/4885
US-20240269156-A1 DISULFIDE CONTAINING THERAPEUTICS P4HB, PDIA5, PDIA4 EHMT2 3151/4885EHMT1 3191/4885APOBEC3G 2768/4885
US-20230028359-A1 NUCLEOTIDE ANALOGUES ITPA, POLB, NUDT1 EHMT2 2878/4885EHMT1 3389/4885APOBEC3G 437/4885
US-11958877-B2 Nucleotide analogues ITPA, POLB, NUDT1 EHMT2 2878/4885EHMT1 3389/4885APOBEC3G 437/4885
US-20230203083-A1 NUCLEOTIDE ANALOGUES ITPA, POLB, NUDT1 EHMT2 2878/4885EHMT1 3389/4885APOBEC3G 437/4885
US-20240174709-A1 NUCLEOTIDE ANALOGUES NUDT1, POLN, TYMP EHMT2 2494/4885EHMT1 2450/4885APOBEC3G 226/4885
US-11878993-B2 Nucleotide analogues ITPA, POLB, NUDT1 EHMT2 2878/4885EHMT1 3389/4885APOBEC3G 437/4885
US-12145960-B2 Nucleotide analogues ITPA, POLB, NUDT1 EHMT2 2878/4885EHMT1 3389/4885APOBEC3G 437/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.