Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.36 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.36 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1324063 | 0.88 | DPP4 (0.39) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL297856 | 0.84 | RAB9A (0.42) | RAB9ATDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL3823515 | 0.79 | TYR (0.36) | ITGB1RAB9AMEN1KMT2ADPP4 | |
| SCHEMBL16817131 | 0.76 | SLC7A5 (0.43) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL23243815 | 0.76 | SLC7A5 (0.46) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL28314060 | 0.75 | PKM (0.50) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL4068426 | 0.74 | ITGB1 (0.49) | ITGB1ITGA5 | |
| SCHEMBL8123546 | 0.74 | PPID (0.41) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL11847587 | 0.71 | PPID (0.43) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL5916451 | 0.71 | ALDH1A1 (0.51) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1595870-A1 | PROCESS FOR PRODUCING PHENYLALANINE DERIVATIVE HAVING QUINAZOLINEDIONE SKELETON AND INTERMEDIATE FOR THE SAME | Ajinomoto Co., Inc. (JP) | 2005-11-16 | — | — | EP | claimed |
| EP-1595870-B1 | PROCESS FOR PRODUCING PHENYLALANINE DERIVATIVE HAVING QUINAZOLINEDIONE SKELETON AND INTERMEDIATE FOR THE SAME | AJINOMOTO KK (JP) | 2015-09-23 | — | — | EP | disclosed |
| US-8318975-B2 | Methods for producing phenylalanine derivatives having a quinazolinedione skeleton and intermediates for production thereof | AJINOMOTO CO., INC. (JP) | 2012-11-27 | — | — | US | disclosed |
| US-20100204505-A1 | METHODS FOR PRODUCING PHENYLALANINE DERIVATIVES HAVING A QUINAZOLINEDIONE SKELETON AND INTERMEDIATES FOR PRODUCTION THEREOF | AJINOMOTO CO. INC (JP) | 2010-08-12 | — | — | US | disclosed |
| US-7737274-B2 | Methods for producing phenylalanine derivatives having a quinazolinedione skeleton and intermediates for production thereof | AJINOMOTO CO., INC. (JP) | 2010-06-15 | — | — | US | disclosed |
| US-20060009476-A1 | Methods for producing phenylalanine derivatives having a quinazolinedione skeleton and intermediates for production thereof | AJINOMOTO CO. INC (JP) | 2006-01-12 | — | — | US | disclosed |
| EP-1595870-A1 | PROCESS FOR PRODUCING PHENYLALANINE DERIVATIVE HAVING QUINAZOLINEDIONE SKELETON AND INTERMEDIATE FOR THE SAME | Ajinomoto Co., Inc. (JP) | 2005-11-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204505-A1 | METHODS FOR PRODUCING PHENYLALANINE DERIVATIVES HAVING A QUINAZOLINEDIONE SKELETON AND INTERMEDIATES FOR PRODUCTION THEREOF | ITGA4, ITGB4, ITGA5 | SLC7A5 92/4885ALPI 1215/4885PKM 723/4885 |
| US-20060009476-A1 | Methods for producing phenylalanine derivatives having a quinazolinedione skeleton and intermediates for production thereof | ITGA4, ITGB4, ITGA5 | SLC7A5 92/4885ALPI 1215/4885PKM 723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.