SCHEMBL3019804

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL118340	0.87	KEAP1 (0.59)	PTGS2HPGDRECQLKEAP1KDM4E
	SCHEMBL3023217	0.85	HPGD (0.57)	PTPN11HPGDRECQLKDM4ELMNA
	SCHEMBL10646367	0.85	HPGD (0.57)	PTGS2HPGDRECQLKEAP1KDM4E
	SCHEMBL2044935	0.82	KIF11 (0.59)	PTGS2HPGDRECQLKEAP1KDM4E
	SCHEMBL21360563	0.80	PTPN11 (0.56)	PTPN11HPGDRARBRARGKDM4E
	SCHEMBL2679567	0.79	TSHR (0.60)	PTPN11RARBRARGCA12CA1
	SCHEMBL3555520	0.78	KDM4E (0.59)	PTGS2HPGDRECQLKEAP1KDM4E
	SCHEMBL13266907	0.77	CA2 (0.45)	KDM4ELMNACA1CA2
	SCHEMBL3555970	0.77	NPC1 (0.61)	HPGDRECQLRARBLMNA
	SCHEMBL10417625	0.76	HPGD (0.56)	PTGS2HPGDRECQLKEAP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.