Formic Acid

Formic Acid

SCHEMBL30201032

CC(CNC(=N)CNc1ccccc1)Oc1cccc(Cl)c1.O=CO

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
LMNA P02545 1/20 0.46
MTNR1A P48039 10/20 0.45
MTNR1B P49286 10/20 0.45
MAPT P10636 1/20 0.43
RAB9A P51151 1/20 0.43
OGG1 O15527 1/20 0.40
SLC6A4 P31645 1/20 0.40
KLKB1 P03952 1/20 0.39
ADRB2 P07550 1/20 0.39
ADRB1 P08588 1/20 0.39
ADRB3 P13945 1/20 0.39
KMT2A Q03164 1/20 0.39
GRK2 P25098 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30201055 0.95 ALDH1A1 (0.47) ALDH1A1L3MBTL1LMNAMTNR1AMTNR1B
SCHEMBL30200879 0.83 MTNR1A (0.55) ALDH1A1L3MBTL1LMNAMTNR1AMTNR1B
SCHEMBL30201042 0.83 MTNR1A (0.56) ALDH1A1LMNAMTNR1AMTNR1BMAPT
SCHEMBL30201393 0.82 MTNR1A (0.48) MTNR1AMTNR1B
SCHEMBL30200758 0.81 MTNR1A (0.47) ALDH1A1L3MBTL1LMNAMTNR1AMTNR1B
SCHEMBL30201017 0.80 MTNR1A (0.45) ALDH1A1L3MBTL1LMNAMTNR1AMTNR1B
SCHEMBL30201025 0.80 ALDH1A1 (0.44) ALDH1A1MTNR1AMTNR1BMAPTKMT2A
SCHEMBL30201185 0.78 MAOB (0.43) ALDH1A1L3MBTL1LMNAMAPTRAB9A
SCHEMBL30200979 0.77 MTNR1A (0.47) ALDH1A1L3MBTL1MTNR1AMTNR1BKMT2A
SCHEMBL30201037 0.73 DRD2 (0.54) LMNARAB9AKLKB1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023028086-A1 COMBINATIONS OF PERIPHERAL 5-HT2A RECEPTOR ANTAGONISTS AND CENTRAL 5-HT2A RECEPTOR AGONISTS GILGAMESH PHARMACEUTICALS, INC. (US) 2023-03-02 WO disclosed