Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 10/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.48 |
| ▸ | CTSK | P43235 | 3/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30201042 | 0.89 | MTNR1A (0.56) | MTNR1AMTNR1BCTSK | |
| SCHEMBL30201055 | 0.87 | ALDH1A1 (0.47) | MTNR1AMTNR1B | |
| SCHEMBL30200758 | 0.87 | MTNR1A (0.47) | MTNR1AMTNR1B | |
| SCHEMBL30201017 | 0.85 | MTNR1A (0.45) | MTNR1AMTNR1BCTSK | |
| Formic Acid SCHEMBL30201032 | 0.82 | ALDH1A1 (0.46) | MTNR1AMTNR1B | |
| SCHEMBL30200979 | 0.82 | MTNR1A (0.47) | MTNR1AMTNR1B | |
| SCHEMBL30201025 | 0.78 | ALDH1A1 (0.44) | MTNR1AMTNR1BCTSKCNR1 | |
| SCHEMBL30201287 | 0.78 | MTNR1A (0.56) | MTNR1AMTNR1B | |
| SCHEMBL30200879 | 0.77 | MTNR1A (0.55) | MTNR1AMTNR1B | |
| SCHEMBL30201012 | 0.75 | MTNR1B (0.55) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023028086-A1 | COMBINATIONS OF PERIPHERAL 5-HT2A RECEPTOR ANTAGONISTS AND CENTRAL 5-HT2A RECEPTOR AGONISTS | GILGAMESH PHARMACEUTICALS, INC. (US) | 2023-03-02 | — | — | WO | disclosed |