Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 10/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30201042 | 0.86 | MTNR1A (0.56) | MTNR1AMTNR1BALDH1A1LMNACTSK | |
| SCHEMBL30201393 | 0.85 | MTNR1A (0.48) | MTNR1AMTNR1BCTSK | |
| SCHEMBL30200758 | 0.84 | MTNR1A (0.47) | MTNR1AMTNR1BALDH1A1LMNAL3MBTL1 | |
| SCHEMBL30201055 | 0.84 | ALDH1A1 (0.47) | MTNR1AMTNR1BALDH1A1LMNAL3MBTL1 | |
| Formic Acid SCHEMBL30201032 | 0.80 | ALDH1A1 (0.46) | MTNR1AMTNR1BALDH1A1LMNAL3MBTL1 | |
| SCHEMBL30200979 | 0.80 | MTNR1A (0.47) | MTNR1AMTNR1BALDH1A1L3MBTL1 | |
| SCHEMBL30201095 | 0.79 | MTNR1A (0.52) | MTNR1AMTNR1BALDH1A1LMNA | |
| SCHEMBL30201287 | 0.76 | MTNR1A (0.56) | MTNR1AMTNR1BALDH1A1NPSR1 | |
| SCHEMBL30201025 | 0.76 | ALDH1A1 (0.44) | MTNR1AMTNR1BALDH1A1CTSK | |
| SCHEMBL30200879 | 0.75 | MTNR1A (0.55) | MTNR1AMTNR1BALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023028086-A1 | COMBINATIONS OF PERIPHERAL 5-HT2A RECEPTOR ANTAGONISTS AND CENTRAL 5-HT2A RECEPTOR AGONISTS | GILGAMESH PHARMACEUTICALS, INC. (US) | 2023-03-02 | — | — | WO | disclosed |