Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4851359 | 0.87 | OPRM1 (0.52) | OPRM1OPRK1KCNH2SMN1; SMN2KMT2A | |
| Trifluoroacetic Acid SCHEMBL30201490 | 0.80 | ARG1 (0.35) | OPRM1OPRK1KCNH2OPRD1 | |
| Trifluoroacetic Acid SCHEMBL30201771 | 0.78 | LTA4H (0.53) | OPRM1OPRK1KCNH2KMT2AMEN1 | |
| Trifluoroacetic Acid SCHEMBL30201435 | 0.78 | LTA4H (0.49) | OPRM1OPRK1KCNH2KMT2AMEN1 | |
| Trifluoroacetic Acid SCHEMBL30201373 | 0.77 | ARG1 (0.38) | OPRM1OPRK1KCNH2OPRD1 | |
| Trifluoroacetic Acid SCHEMBL30201500 | 0.77 | CYP3A4 (0.39) | SMN1; SMN2CYP2D6CYP2C19ALDH1A1CYP2C9 | |
| SCHEMBL11236040 | 0.76 | HTT (0.44) | OPRM1OPRK1KCNH2SMN1; SMN2KMT2A | |
| Trifluoroacetic Acid SCHEMBL30201583 | 0.76 | LTA4H (0.48) | OPRM1OPRK1KCNH2SMN1; SMN2KMT2A | |
| Trifluoroacetic Acid SCHEMBL30201437 | 0.76 | ARG1 (0.54) | OPRM1OPRK1KCNH2KMT2AMEN1 | |
| Trifluoroacetic Acid SCHEMBL30201455 | 0.76 | ARG1 (0.54) | OPRM1OPRK1KCNH2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009330-A1 | SEROTONIN 5-HT2B INHIBITORY COMPOUNDS | ZOETIS SERVICES LLC (US) | 2023-02-02 | — | — | WO | disclosed |