Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.45 |
| ▸ | DRD4 | P21917 | 3/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ARG1 | P05089 | 2/20 | 0.43 |
| ▸ | ARG2 | P78540 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30201437 | 0.90 | ARG1 (0.54) | LTA4HOPRK1DRD2DRD4DRD3 | |
| Trifluoroacetic Acid SCHEMBL30201455 | 0.90 | ARG1 (0.54) | LTA4HOPRK1DRD2DRD4DRD3 | |
| Trifluoroacetic Acid SCHEMBL30201771 | 0.88 | LTA4H (0.53) | LTA4HOPRK1KCNH2OPRM1MEN1 | |
| SCHEMBL30833222 | 0.87 | DRD2 (0.51) | LTA4HOPRK1DRD2DRD4DRD3 | |
| SCHEMBL3880873 | 0.87 | DRD2 (0.51) | LTA4HOPRK1DRD2DRD4DRD3 | |
| SCHEMBL3880869 | 0.87 | DRD2 (0.51) | LTA4HOPRK1DRD2DRD4DRD3 | |
| Trifluoroacetic Acid SCHEMBL30201435 | 0.86 | LTA4H (0.49) | LTA4HOPRK1KCNH2OPRM1MEN1 | |
| SCHEMBL10817485 | 0.82 | OPRK1 (0.52) | OPRK1DRD2DRD4DRD3SLC6A2 | |
| Trifluoroacetic Acid SCHEMBL30201381 | 0.79 | KCNH2 (0.53) | OPRK1KCNH2OPRM1ARG1ARG2 | |
| Trifluoroacetic Acid SCHEMBL1920766 | 0.78 | SIGMAR1 (0.53) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009330-A1 | SEROTONIN 5-HT2B INHIBITORY COMPOUNDS | ZOETIS SERVICES LLC (US) | 2023-02-02 | — | — | WO | disclosed |