Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | TTR | P02766 | 2/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | HBB | P68871 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Marcanin A SCHEMBL29923975 | 0.93 | RAB9A (0.47) | TNKS2CYP1A2CYP2C19TTRCYP1A1 | |
| SCHEMBL14873867 | 0.77 | CYP1A2 (0.41) | TNKS2CYP1A2CYP2C19ALDH1A1TSHR | |
| SCHEMBL7818677 | 0.72 | CYP1A2 (0.33) | TNKS2CYP1A2CYP2C19ALDH1A1SMN1; SMN2 | |
| SCHEMBL6905929 | 0.69 | ELANE (0.52) | CYP1A2CYP2C19TTRCYP1A1RAB9A | |
| SCHEMBL30886455 | 0.69 | ALDH1A1 (0.67) | CYP1A2CYP2C19TTRCYP1A1RAB9A | |
| SCHEMBL55743 | 0.69 | ALDH1A1 (0.67) | CYP1A2CYP2C19TTRCYP1A1RAB9A | |
| SCHEMBL8668950 | 0.68 | ELANE (0.53) | CYP1A2TTRCYP1A1RAB9APOLB | |
| SCHEMBL6503650 | 0.68 | MAOA (0.54) | TNKS2CYP1A2RAB9APOLBAPAF1 | |
| SCHEMBL20415202 | 0.68 | TNKS2 (0.37) | TNKS2CYP1A2CYP2C19ALDH1A1TSHR | |
| SCHEMBL8771223 | 0.68 | ELANE (0.53) | CYP1A2TTRCYP1A1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3768830-B1 | CANCER THERAPY | VALO THERAPEUTICS OY (FI) | 2023-01-25 | — | — | EP | claimed |