Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | ARG1 | P05089 | 2/20 | 0.39 |
| ▸ | ARG2 | P78540 | 2/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30201437 | 0.78 | ARG1 (0.54) | ARG1ARG2KCNH2LTA4H | |
| Trifluoroacetic Acid SCHEMBL30201455 | 0.78 | ARG1 (0.54) | ARG1ARG2KCNH2LTA4H | |
| Trifluoroacetic Acid SCHEMBL30201583 | 0.78 | LTA4H (0.48) | ARG1ARG2KCNH2LTA4H | |
| Trifluoroacetic Acid SCHEMBL30201771 | 0.77 | LTA4H (0.53) | SIGMAR1ARG1ARG2KCNH2LTA4H | |
| Trifluoroacetic Acid SCHEMBL30201435 | 0.75 | LTA4H (0.49) | ARG1ARG2KCNH2LTA4H | |
| SCHEMBL30201517 | 0.73 | SMYD3 (0.52) | — | |
| Trifluoroacetic Acid SCHEMBL30201381 | 0.71 | KCNH2 (0.53) | ARG1ARG2KCNH2 | |
| SCHEMBL4843953 | 0.69 | ACHE (0.49) | ACHECCR3 | |
| SCHEMBL22584711 | 0.68 | LTA4H (0.63) | FAAHPARP1PARP2ACHEHTR4 | |
| Acetic Acid SCHEMBL8400064 | 0.67 | HCRTR1 (0.38) | FAAHPARP1PARP2KCNH2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009330-A1 | SEROTONIN 5-HT2B INHIBITORY COMPOUNDS | ZOETIS SERVICES LLC (US) | 2023-02-02 | — | — | WO | disclosed |