Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ARG1 | P05089 | 1/20 | 0.41 |
| ▸ | ARG2 | P78540 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30201435 | 0.85 | LTA4H (0.49) | KCNH2OPRK1OPRM1F2F10 | |
| Trifluoroacetic Acid SCHEMBL30201532 | 0.80 | DPP4 (0.41) | KCNH2OPRK1OPRM1F2F10 | |
| Trifluoroacetic Acid SCHEMBL30201455 | 0.79 | ARG1 (0.54) | KCNH2OPRK1OPRM1POLBARG1 | |
| Trifluoroacetic Acid SCHEMBL30201437 | 0.79 | ARG1 (0.54) | KCNH2OPRK1OPRM1POLBARG1 | |
| Trifluoroacetic Acid SCHEMBL30201583 | 0.79 | LTA4H (0.48) | KCNH2OPRK1OPRM1ARG1ARG2 | |
| Trifluoroacetic Acid SCHEMBL30201771 | 0.78 | LTA4H (0.53) | KCNH2OPRK1OPRM1ARG1ARG2 | |
| Trifluoroacetic Acid SCHEMBL30201424 | 0.78 | OPRM1 (0.52) | KCNH2OPRK1OPRM1F2F10 | |
| Trifluoroacetic Acid SCHEMBL30201490 | 0.75 | ARG1 (0.35) | KCNH2OPRK1OPRM1ARG1ARG2 | |
| Trifluoroacetic Acid SCHEMBL30201414 | 0.74 | OPRM1 (0.51) | KCNH2OPRK1OPRM1F2F10 | |
| SCHEMBL15021133 | 0.73 | CHRM2 (0.58) | KCNH2OPRK1OPRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009330-A1 | SEROTONIN 5-HT2B INHIBITORY COMPOUNDS | ZOETIS SERVICES LLC (US) | 2023-02-02 | — | — | WO | disclosed |