Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 2/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TACR3 | P29371 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21170645 | 0.84 | HRH3 (0.54) | L3MBTL1POLBTDP1KMT2AMEN1 | |
| SCHEMBL14117676 | 0.84 | HRH3 (0.54) | SIGMAR1L3MBTL1POLBTDP1KMT2A | |
| SCHEMBL12093445 | 0.84 | PKM (0.67) | POLBTDP1KMT2AMEN1RAB9A | |
| SCHEMBL4751256 | 0.84 | HSP90AA1 (0.55) | POLBTDP1KMT2ARAB9AHRH3 | |
| SCHEMBL29908037 | 0.83 | HPGD (0.59) | L3MBTL1POLBTDP1KMT2AMEN1 | |
| SCHEMBL28837075 | 0.83 | HPGD (0.59) | L3MBTL1POLBTDP1KMT2AMEN1 | |
| SCHEMBL17925958 | 0.83 | SIGMAR1 (0.51) | SIGMAR1L3MBTL1HPGDDDB1CRBN | |
| SCHEMBL16026473 | 0.83 | HSP90AA1 (0.53) | L3MBTL1POLBTDP1KMT2AMEN1 | |
| SCHEMBL17533885 | 0.82 | TSHR (0.56) | L3MBTL1POLBTDP1KMT2AMEN1 | |
| SCHEMBL17850234 | 0.82 | POLB (0.59) | L3MBTL1POLBTDP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110396067-B | 1, 4-disubstituted-2-piperazinone compound and pharmaceutical application thereof | 复旦大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-104046246-B | The chemical-mechanical planarization of tungsten-containing substrate | 气体产品与化学公司 | 2016-06-15 | — | — | CN | disclosed |
| US-7566717-B2 | Substituted heterocyclic compounds | GILEAD SCIENCES, INC. (US) | 2009-07-28 | — | — | US | disclosed |
| US-20080275238-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS | PALLE VENKATA | 2008-11-06 | — | — | US | disclosed |
| EP-0107423-B1 | NOVEL CHROMANS AND CHROMENES | BEECHAM GROUP PLC (GB) | 1986-07-23 | — | — | EP | disclosed |
| US-4496565-A | HYPOTENSIVE AGENTS | BEECHAM GROUP P.L.C. (GB) | 1985-01-29 | — | — | US | disclosed |
| EP-0107423-A1 | Novel chromans and chromenes | BEECHAM GROUP PLC (GB) | 1984-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275238-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS | KCNH1, SDHA, COQ8A | SIGMAR1 4373/4885L3MBTL1 1085/4885POLB 2485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.