Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL302065

N.c1ccc(-c2ccc(N(c3ccccc3)c3ccccc3)c(-c3ccccc3)c2-c2ccccc2)cc1

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.33
TDP1 Q9NUW8 2/20 0.33
MAPT P10636 2/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
LMNA P02545 1/20 0.32
HTT P42858 1/20 0.32
CTRC Q99895 1/20 0.32
ALOX5 P09917 1/20 0.31
BACE1 P56817 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
RXRA P19793 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7714905 0.98 ALDH1A1 (0.34) ALDH1A1TDP1MAPTKDM4ECYP1A2
SCHEMBL360294 0.93 L3MBTL1 (0.39) ALDH1A1TDP1MAPTKDM4ECYP1A2
SCHEMBL8749954 0.93 L3MBTL1 (0.39) ALDH1A1TDP1MAPTKDM4ECYP1A2
SCHEMBL27269782 0.91 ALDH1A1 (0.34) ALDH1A1TDP1MAPTKDM4ECYP1A2
SCHEMBL297638 0.88 ALDH1A1 (0.48) ALDH1A1TDP1MAPTKDM4ECYP1A2
SCHEMBL27269850 0.87 MAPT (0.37) ALDH1A1TDP1MAPTKDM4ECYP1A2
SCHEMBL5817829 0.87 MAPT (0.32) ALDH1A1TDP1MAPTKDM4ECYP1A2
SCHEMBL31501053 0.86 NPC1 (0.34) ALDH1A1TDP1MAPTKDM4ECYP2C19
SCHEMBL30486687 0.86 RXRA (0.31) RXRARXRB
SCHEMBL29011927 0.86 RXRA (0.31) RXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1791926-B1 NEW COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME(10) LG CHEMICAL LTD (KR) 2016-08-31 EP disclosed
EP-1794259-B1 NEW COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME(9) LG CHEMICAL LTD (KR) 2012-01-11 EP disclosed
US-7842405-B2 a fluorene derivative capable of significantly improving a lifespan, efficiency, and electrochemical and thermal stability LG CHEM, LTD. (KR) 2010-11-30 US disclosed
US-7816019-B2 Compound and organic light emitting device using the same LG CHEM, LTD. (KR) 2010-10-19 US disclosed
US-7811682-B2 Compound and organic light emitting device using the same LG CHEM, LTD. (KR) 2010-10-12 US disclosed
EP-1791929-B1 NEW COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME(5) LG CHEMICAL LTD (KR) 2010-09-01 EP disclosed
US-20090045721-A1 Compound and organic light emitting device using the same LG CHEM, LTD. (KR) 2009-02-19 US disclosed
US-20080303434-A1 Compound and Organic Light Emitting Device Using the Same LG CHEM, LTD. (KR) 2008-12-11 US disclosed
EP-1791929-A4 NEW COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME(5) LG CHEMICAL LTD (KR) 2008-11-05 EP disclosed
EP-1794259-A4 NEW COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME(9) LG CHEMICAL LTD (KR) 2008-06-11 EP disclosed
EP-1791926-A4 NEW COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME(10) LG CHEMICAL LTD (KR) 2008-06-11 EP disclosed
US-20080093982-A1 Compound and Organic Light Emitting Device Using the Same LG CHEM, LTD. (KR) 2008-04-24 US disclosed
EP-1794259-A1 NEW COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME(9) LG Chem, Ltd. (KR) 2007-06-13 EP disclosed
EP-1791929-A1 NEW COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME(5) LG Chem, Ltd. (KR) 2007-06-06 EP disclosed
EP-1791926-A1 NEW COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME(10) LG Chem, Ltd. (KR) 2007-06-06 EP disclosed
WO-2006080644-A1 NEW COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME(5) LG CHEM. LTD. (KR) 2006-08-03 WO disclosed
WO-2006080645-A1 NEW COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME(9) LG CHEM. LTD. (KR) 2006-08-03 WO disclosed
WO-2006033564-A1 NEW COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME(10) LG CHEM. LTD. (KR) 2006-03-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080303434-A1 Compound and Organic Light Emitting Device Using the Same PPOX, CRY1, CRY2 ALDH1A1 318/4885TDP1 1026/4885MAPT 100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.