Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | NPY1R | P25929 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | NPY2R | P49146 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | THPO | P40225 | 1/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30208541 | 0.93 | ADORA2A (0.58) | LMNAALDH1A1GLAPMP22SMN1; SMN2 | |
| SCHEMBL30208574 | 0.91 | LMNA (0.60) | LMNAALDH1A1GLAPMP22SMN1; SMN2 | |
| SCHEMBL30208584 | 0.87 | ADORA2A (0.59) | LMNAALDH1A1GLAPMP22SMN1; SMN2 | |
| SCHEMBL2480941 | 0.86 | ADORA2A (0.62) | ALDH1A1PMP22TSHRNFKB1ADORA2A | |
| SCHEMBL854222 | 0.86 | ADORA3 (0.70) | LMNAALDH1A1GLAPMP22SMN1; SMN2 | |
| SCHEMBL29047905 | 0.84 | ADORA2A (0.60) | ALDH1A1PMP22TSHRNFKB1ADORA2A | |
| SCHEMBL29047902 | 0.84 | ADORA2A (0.60) | ALDH1A1PMP22TSHRNFKB1ADORA2A | |
| SCHEMBL30208465 | 0.84 | HIF1A (0.53) | SLC29A1ADORA3 | |
| SCHEMBL3499233 | 0.84 | ADORA2A (0.64) | ALDH1A1PMP22TSHRNFKB1ADORA2A | |
| SCHEMBL3499237 | 0.84 | ADORA2A (0.64) | ALDH1A1PMP22TSHRNFKB1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023001982-A1 | MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION | UNIVERSITÄT BASEL (CH) | 2023-01-26 | — | — | WO | claimed |
| WO-2023001982-A1 | MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION | UNIVERSITÄT BASEL (CH) | 2023-01-26 | — | — | WO | disclosed |