Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.57 |
| ▸ | QARS1 | P47897 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30208537 | 0.93 | LMNA (0.58) | ADORA2AADORA2BADORA1ALDH1A1LMNA | |
| SCHEMBL30208584 | 0.91 | ADORA2A (0.59) | ADORA2AADORA2BADORA1ALDH1A1LMNA | |
| SCHEMBL3898255 | 0.88 | P2RY12 (0.65) | ADORA1QARS1SMN1; SMN2 | |
| SCHEMBL30208574 | 0.87 | LMNA (0.60) | ADORA2AADORA2BADORA1ALDH1A1LMNA | |
| SCHEMBL2480941 | 0.86 | ADORA2A (0.62) | ADORA2AADORA2BALDH1A1PMP22 | |
| SCHEMBL28477260 | 0.85 | ADORA2A (0.67) | ADORA2AADORA2BADORA1ALDH1A1LMNA | |
| SCHEMBL29047905 | 0.84 | ADORA2A (0.60) | ADORA2AADORA2BALDH1A1PMP22 | |
| SCHEMBL29047902 | 0.84 | ADORA2A (0.60) | ADORA2AADORA2BALDH1A1PMP22 | |
| SCHEMBL30208581 | 0.84 | HIF1A (0.53) | QARS1ADORA3 | |
| SCHEMBL854222 | 0.84 | ADORA3 (0.70) | ADORA2AADORA2BADORA1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023001982-A1 | MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION | UNIVERSITÄT BASEL (CH) | 2023-01-26 | — | — | WO | claimed |
| WO-2023001982-A1 | MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION | UNIVERSITÄT BASEL (CH) | 2023-01-26 | — | — | WO | disclosed |