SCHEMBL301844

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL303366	0.91	L3MBTL1 (0.56)	KEAP1NFE2L2L3MBTL1MAPTTSHR
	SCHEMBL304757	0.87	L3MBTL1 (0.50)	KEAP1NFE2L2L3MBTL1MAPTTSHR
	SCHEMBL302098	0.86	KEAP1 (0.49)	KEAP1NFE2L2L3MBTL1MAPTMMP2
	SCHEMBL3377911	0.84	MAPT (0.54)	L3MBTL1MAPTTP53MCL1MEN1
	SCHEMBL3380874	0.83	NR3C1 (0.54)	KEAP1NFE2L2MAPTMMP13TP53
	SCHEMBL303525	0.83	KMT2A (0.53)	L3MBTL1MAPTTSHRTP53MEN1
	SCHEMBL303293	0.79	GAA (0.63)	MAPTMEN1KMT2AGAAHTT
	SCHEMBL302950	0.79	NR3C1 (0.55)	KEAP1NFE2L2MAPTTP53MCL1
	SCHEMBL3380436	0.78	NR1H2 (0.45)	MAPTTP53MCL1MEN1KMT2A
	SCHEMBL301986	0.78	NAMPT (0.51)	KEAP1NFE2L2MAPTMMP13MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.