SCHEMBL4634722

SCHEMBL4634722

N=C([S])c1ccccc1[C]=O

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
ALDH1A1 P00352 1/20 0.32
ALOX15 P16050 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL302106 0.80 NPC1 (0.33) NPC1RAB9AALDH1A1ALOX15
SCHEMBL6808280 0.78 NPC1 (0.40) NPC1RAB9AALDH1A1ALOX15
SCHEMBL896901 0.76 NPC1 (0.41) NPC1RAB9AALDH1A1ALOX15
SCHEMBL4632881 0.75 NPC1 (0.31) NPC1RAB9AALDH1A1ALOX15
SCHEMBL5565721 0.74 NR4A1 (0.31) NPC1RAB9A
SCHEMBL1157075 0.73 ALDH1A1 (0.40) NPC1RAB9AALDH1A1ALOX15
SCHEMBL8385 0.73 ALDH1A1 (0.59) NPC1RAB9AALDH1A1ALOX15
SCHEMBL11594420 0.71 NPC1 (0.60) NPC1RAB9AALDH1A1ALOX15
SCHEMBL101186 0.71 ALDH1A1 (0.50) NPC1RAB9AALDH1A1ALOX15
SCHEMBL11418729 0.71 ALDH1A1 (0.39) NPC1RAB9AALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7405030-B2 Imide compound and optical recording media made by using the same MITSUI CHEMICALS, INC. (JP) 2008-07-29 US disclosed
EP-1930339-A2 Imide compound MITSUI CHEMICALS, INC. (JP) 2008-06-11 EP disclosed
US-20070259151-A1 Imide compound and optical recording media made by using the same MITSUI CHEMICALS, INC. (JP) 2007-11-08 US disclosed
US-7259260-B2 Imide compound and optical recording media made by using the same MITSUI CHEMICALS, INC. (JP) 2007-08-21 US disclosed
US-20050208425-A1 Imide compound and optical recording media made by using the same YAMAMOTO CHEMICALS, INC. (JP) 2005-09-22 US disclosed
EP-1445115-A1 IMIDE COMPOUNDS AND OPTICAL RECORDING MEDIA MADE BY USING THE SAME Mitsui Chemicals, Inc. (JP) 2004-08-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050208425-A1 Imide compound and optical recording media made by using the same CRY1, MTNR1A, TRPA1 NPC1 2019/4885RAB9A 311/4885ALDH1A1 1336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.