SCHEMBL30219415

SCHEMBL30219415

ON=C(c1ccc(Cc2ccccc2)cc1)C(F)(F)F

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.50
ALDH1A1 P00352 1/20 0.50
ALOX15 P16050 1/20 0.50
HSD17B10 Q99714 1/20 0.50
LMNA P02545 2/20 0.46
PLA2G10 O15496 1/20 0.46
PLA2G2A P14555 1/20 0.46
CALM1 P0DP23 1/20 0.43
SLC22A2 O15244 1/20 0.41
SRD5A2 P31213 2/20 0.39
CES1 P23141 2/20 0.39
IDH1 O75874 1/20 0.39
PDK2 Q15119 1/20 0.39
MAPK1 P28482 1/20 0.38
CASP3 P42574 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CYP2C9 P11712 1/20 0.38
GRIN2B Q13224 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1669122 0.82 ALDH1A1 (0.57) GAAALDH1A1ALOX15HSD17B10LMNA
SCHEMBL7246133 0.82 ALDH1A1 (0.57) GAAALDH1A1ALOX15HSD17B10LMNA
SCHEMBL9799638 0.82 ALDH1A1 (0.57) GAAALDH1A1ALOX15HSD17B10LMNA
SCHEMBL13410378 0.81 LMNA (0.46) GAAALDH1A1ALOX15HSD17B10LMNA
SCHEMBL30219433 0.79 NR4A2 (0.55) GAALMNASRD5A2CASP3SENP7
SCHEMBL7195733 0.75 ALDH1A1 (0.50) GAAALDH1A1ALOX15HSD17B10LMNA
SCHEMBL7249591 0.75 GAA (0.50) GAAALDH1A1ALOX15HSD17B10SRD5A2
SCHEMBL7195730 0.75 ALDH1A1 (0.50) GAAALDH1A1ALOX15HSD17B10LMNA
SCHEMBL7249593 0.75 GAA (0.50) GAAALDH1A1ALOX15HSD17B10SRD5A2
SCHEMBL30219465 0.75 PKM (0.53) GAAALDH1A1ALOX15HSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11884839-B2 Acetal-protected silanol group-containing polysiloxane composition NISSAN CHEMICAL CORPORATION (JP) 2024-01-30 US disclosed
US-20230125270-A1 RADIATION SENSITIVE COMPOSITION NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2023-04-27 US disclosed
US-11561472-B2 Radiation sensitive composition NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2023-01-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11561472-B2 Radiation sensitive composition RER1, RAD1, RAD51 GAA 1412/4885ALDH1A1 2201/4885ALOX15 3772/4885
US-20230125270-A1 RADIATION SENSITIVE COMPOSITION XRCC6, RAD50, XRCC5 GAA 4626/4885ALDH1A1 1388/4885ALOX15 1906/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.