Sugi Predict

Sugi Predict / Compounds / SCHEMBL302274

SCHEMBL302274

SCHEMBL302274

CC/C=C\CC/C=C/C(=O)NCC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CNR1 P21554 6/20 0.47
▸ CNR2 P34972 4/20 0.47
▸ PPARA Q07869 3/20 0.43
▸ TRPA1 O75762 1/20 0.40
▸ TRPV1 Q8NER1 1/20 0.40
▸ ALDH1A1 P00352 4/20 0.40
▸ FAAH O00519 1/20 0.40
▸ PPARG P37231 3/20 0.39
▸ CYP19A1 P11511 2/20 0.39
▸ RXRA P19793 2/20 0.39
▸ OXER1 Q8TDS5 2/20 0.39
▸ FFAR1 O14842 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ TAS1R3 Q7RTX0 1/20 0.39
▸ TAS1R1 Q7RTX1 1/20 0.39
▸ PPARD Q03181 2/20 0.39
▸ PTGS1 P23219 2/20 0.37
▸ F7 P08709 1/20 0.37
▸ ADORA3 P0DMS8 1/20 0.37
▸ F3 P13726 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3951480 1.00 CNR1 (0.47) CNR1CNR2PPARATRPA1TRPV1
SCHEMBL4888803 1.00 CNR1 (0.47) CNR1CNR2PPARATRPA1TRPV1
SCHEMBL4884486 0.92 ALDH1A1 (0.44) CNR1CNR2PPARAALDH1A1PPARG
SCHEMBL4884498 0.92 ALDH1A1 (0.44) CNR1CNR2PPARAALDH1A1PPARG
SCHEMBL28708124 0.87 — —
SCHEMBL12127403 0.87 — —
SCHEMBL13123961 0.87 — —
SCHEMBL4406724 0.84 CNR1 (0.45) CNR1CNR2PPARATRPA1TRPV1
SCHEMBL6370037 0.83 TAS1R3 (0.55) CNR1CNR2PPARATRPA1TRPV1
SCHEMBL2784701 0.83 PSMB11 (0.42) CNR1CNR2TRPA1TRPV1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3494104-B1 WARMING SENSATION COMPOUNDS TAKASAGO PERFUMERY CO LTD (JP) 2023-11-15 — — EP claimed
CN-110082441-B Method and kit for detecting forbidden essences 中国检验检疫科学研究院 2022-03-01 — — CN claimed
CN-109803948-B Warming sensation compound 高砂香料工业株式会社 2022-03-01 — — CN claimed
US-11059771-B2 Warming sensation compounds TAKASAGO INTERNATIONAL CORPORATION (JP) 2021-07-13 — — US claimed
US-11034644-B2 — — 2021-06-15 — — US claimed
EP-3494104-A1 WARMING SENSATION COMPOUNDS Takasago International Corporation (JP) 2019-06-12 — — EP claimed
US-20190169111-A1 WARMING SENSATION COMPOUNDS TAKASAGO INTERNATIONAL CORPORATION (JP) 2019-06-06 — — US claimed
WO-2018027202-A1 WARMING SENSATION COMPOUNDS TAKASAGO INTERNATIONAL CORPORATION (USA) (US) 2018-02-08 — — WO claimed
EP-2742983-B1 Method for isolating fragrance and flavour compounds SYMRISE AG (DE) 2017-08-23 — — EP claimed
EP-1863466-B1 SYNERGISTIC SALIVATION COMPONENTS TAKASAGO INT CORP (USA) (US) 2017-08-09 — — EP claimed
US-20140099391-A1 SYNERGISTIC SALIVATION AGENTS TAKASAGO INTERNATIONAL CORP. (USA) (US) 2014-04-10 — — US claimed
EP-2529632-B1 Cinnamic acid amides as spicy flavour agents SYMRISE AG (DE) 2013-08-28 — — EP claimed
US-20120308703-A1 Cinnamamides as savory flavorings SYMRISE AG (DE) 2012-12-06 — — US claimed
EP-2529632-A1 Cinnamic acid amides as spicy flavour agents Symrise AG (DE) 2012-12-05 — — EP claimed
EP-1863466-A2 SYNERGISTIC SALIVATION COMPONENTS Takasago International Corporation (USA) (US) 2007-12-12 — — EP claimed
US-20070178123-A1 FLAVOR-ENHANCING COMPOSITIONS, METHOD OF MANUFACTURE, AND METHODS OF USE KRAFT FOODS GLOBAL BRANDS LLC 2007-08-02 — — US claimed
WO-2006112961-A2 SYNERGISTIC SALIVATION COMPONENTS TAKASAGO INTERNATIONAL CORP. (USA) (US) 2006-10-26 — — WO claimed
US-20060204551-A1 Synergistic salivation agents TAKASAGO INTERNATIONAL CORP. (US) 2006-09-14 — — US claimed
EP-1473287-A2 Alkyldienamides exhibiting taste and sensory effect in flavor compositions INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2004-11-03 — — EP claimed
US-20040202619-A1 Alkyldienamides exhibiting taste and sensory effect in flavor compositions INTERNATIONAL FLAVORS & FRAGRANCES INC. 2004-10-14 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040202619-A1 Alkyldienamides exhibiting taste and sensory effect in flavor compositions TAS2R5, TAS2R4, TAS2R3 CNR1 870/4885CNR2 456/4885PPARA 3074/4885
US-20140099391-A1 SYNERGISTIC SALIVATION AGENTS TAS2R30, TAS2R50, TAS1R3 CNR1 3588/4885CNR2 3900/4885PPARA 3265/4885
US-11059771-B2 Warming sensation compounds TRPA1, TRPV1, TRPV4 CNR1 543/4885CNR2 383/4885PPARA 395/4885
US-11034644-B2 — TRPA1, TRPV1, TRPV5 CNR1 784/4885CNR2 519/4885PPARA 369/4885
US-20190169111-A1 WARMING SENSATION COMPOUNDS TRPA1, TRPV1, TRPV4 CNR1 543/4885CNR2 383/4885PPARA 395/4885
US-20060204551-A1 Synergistic salivation agents TAS2R30, TAS2R50, TAS1R3 CNR1 3588/4885CNR2 3900/4885PPARA 3265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.