Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30228280 | 1.00 | CHRM2 (0.51) | CHRM2CHRM4CHRM1CHRM3ACHE | |
| SCHEMBL31710619 | 0.89 | ALDH1A1 (0.43) | CHRM2CHRM4CHRM1CHRM3ACHE | |
| SCHEMBL30228377 | 0.89 | ALDH1A1 (0.43) | CHRM2CHRM4CHRM1CHRM3ACHE | |
| SCHEMBL30228588 | 0.86 | MEN1 (0.51) | ALDH1A1LMNAL3MBTL1HPGDHTT | |
| SCHEMBL30228426 | 0.83 | ALDH1A1 (0.52) | ALDH1A1LMNAL3MBTL1HPGDHSD17B10 | |
| SCHEMBL30227980 | 0.81 | NPC1 (0.45) | ALDH1A1HPGDHSD17B10RAB9ATDP1 | |
| SCHEMBL30228133 | 0.80 | KCNA3 (0.42) | ALDH1A1HPGDRAB9ATDP1KCNA3 | |
| SCHEMBL30228032 | 0.79 | PLA2G7 (0.62) | ALDH1A1LMNAL3MBTL1HPGDHTT | |
| SCHEMBL30228153 | 0.79 | CA12 (0.53) | ALDH1A1LMNAL3MBTL1HPGDHTT | |
| SCHEMBL30228560 | 0.78 | RAB9A (0.47) | ALDH1A1LMNAL3MBTL1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034346-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2023-03-09 | — | — | WO | disclosed |