SCHEMBL302283

SCHEMBL302283

O=Cc1cc(C=O)nc(C=O)n1

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 1/20 0.40
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8461698 0.73 CCR1 (0.32) CCR1
SCHEMBL302424 0.71 ADORA2A (0.50) ALDH1A1
SCHEMBL1310535 0.71 CCR1 (0.40) CCR1ALDH1A1
SCHEMBL6750865 0.69 CCR1 (0.44) CCR1ALDH1A1
SCHEMBL5674970 0.69 S1PR2 (0.34) ALDH1A1
SCHEMBL11186411 0.69 LMNA (0.42) ALDH1A1
SCHEMBL10974012 0.69 NOS2 (0.43) CCR1ALDH1A1
SCHEMBL2742823 0.69 ERN1 (0.32)
SCHEMBL2492679 0.69 CCR1 (0.39) CCR1ALDH1A1
SCHEMBL12190768 0.69 CCR1 (0.39) CCR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2012500859-A 2012-01-12 JP claimed
US-20110150803-A1 EQUILIBRATED DYNAMIC MIXTURES CONTAINING STABILIZED HEMIACETALS FOR THE CONTROLLED RELEASE OF ACTIVE ALCOHOLS FIRMENICH SA (CH) 2011-06-23 US claimed
EP-2318100-A1 EQUILIBRATED DYNAMIC MIXTURES CONTAINING STABILIZED HEMIACETALS FOR THE CONTROLLED RELEASE OF ACTIVE ALCOHOLS Firmenich S.A. (CH) 2011-05-11 EP claimed
WO-2010020954-A1 EQUILIBRATED DYNAMIC MIXTURES CONTAINING STABILIZED HEMIACETALS FOR THE CONTROLLED RELEASE OF ACTIVE ALCOHOLS FIRMENICH SA (CH) 2010-02-25 WO claimed
CN-1894234-A Dipeptidyl peptidase inhibitors SYRRX INC (JP) 2007-01-10 CN claimed
CN-1473153-A Hetero-anellated ortho-aminophenols 克莱里安特财务(BVI)有限公司 2004-02-04 CN claimed
CN-119285001-A Organic wastewater treatment agent and preparation method thereof 武汉市欣慕沛环保有限公司 2025-01-10 CN disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
CN-107075269-B Stabilization of C.I. Pigment Yellow 139 巴斯夫欧洲公司 2019-08-02 CN disclosed
CN-106622362-B The preparation method and its spare magnetic acidity nanometer material catalyst processed of a kind of 5- arlydene barbituric acid derivatives, the derivative 马鞍山市泰博化工科技有限公司 2019-06-14 CN disclosed
CN-107427033-A Flavour composition and pet food comprising same 马斯公司 2017-12-01 CN disclosed
CN-107249349-A Methods for modulating taste receptors 马斯公司 2017-10-13 CN disclosed
CN-107074847-A Novel pyridopyrimidine derivative compound 生物实验萨纽斯药物有限公司 2017-08-18 CN disclosed
CN-1473153-A Hetero-anellated ortho-aminophenols 克莱里安特财务(BVI)有限公司 2004-02-04 CN disclosed
CN-1374954-A Novel pyrimidine-2, 4, 6-trione derivatives, process for their production and pharmaceutical agents containing these compounds HOFFMANN LA ROCHE (CH) 2002-10-16 CN disclosed
CN-1368963-A Pyrimidine-2,4,6-trione metalloproteinase inhibitors PFIZER PROD INC (US) 2002-09-11 CN disclosed
CN-1268126-A Pyrimidin-2,4,6-trion derivatives and their use as metalloprotease-inhibitors ROCHE DIAGNOSTICS GMBH (DE) 2000-09-27 CN disclosed
CN-1034806-C Process for preparing pyrimidinetrione derivatives SAPOS SA (CH) 1997-05-07 CN disclosed
CN-1121070-A Process for preparing pyrimidinetrione derivatives SAPOS SA (CH) 1996-04-24 CN disclosed
CN-1054592-A PROCESS FOR PREPARING PYRIMIDINETRIONE DERIVATIVES SAPOS SA (CH) 1991-09-18 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110150803-A1 EQUILIBRATED DYNAMIC MIXTURES CONTAINING STABILIZED HEMIACETALS FOR THE CONTROLLED RELEASE OF ACTIVE ALCOHOLS ADH5, ADH1C, ADH1A CCR1 4003/4885ALDH1A1 16/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.