Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1989695 | 0.82 | LMNA (0.34) | PKMALDH1A1POLBMAPTL3MBTL1 | |
| SCHEMBL28999268 | 0.80 | RAB9A (0.36) | PKMALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL5199582 | 0.79 | MAOA (0.39) | PKMALDH1A1POLBSMN1; SMN2MAPT | |
| SCHEMBL2417409 | 0.77 | DUT (0.34) | ALDH1A1MAPTTDP1LMNADUT | |
| SCHEMBL12002519 | 0.73 | PYCR1 (0.39) | POLBSMN1; SMN2MAPTHPGDPABPC1 | |
| SCHEMBL25259307 | 0.72 | PKM (0.41) | PKMALDH1A1POLBSMN1; SMN2MAPT | |
| SCHEMBL30228760 | 0.71 | CA1 (0.39) | ALDH1A1SMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL2414603 | 0.71 | DUT (0.39) | PKMALDH1A1POLBSMN1; SMN2MAPT | |
| SCHEMBL3863346 | 0.70 | HTR1D (0.33) | DUT | |
| SCHEMBL8586241 | 0.69 | DUT (0.36) | ALDH1A1HPGDL3MBTL1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916756-A | Sulfone derivative | 豪夫迈·罗氏有限公司 | 2023-04-04 | — | — | CN | disclosed |