Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | NCF1 | P14598 | 1/20 | 0.49 |
| ▸ | ME2 | P23368 | 1/20 | 0.48 |
| ▸ | ME1 | P48163 | 1/20 | 0.48 |
| ▸ | ME3 | Q16798 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20075898 | 0.88 | ALDH1A1 (0.52) | MAPTGAANCF1ME2ME1 | |
| SCHEMBL18551215 | 0.86 | MAPT (0.46) | MAPTGAANCF1ME2ME1 | |
| SCHEMBL8230640 | 0.81 | GFER (0.59) | MAPTGAAGFERKDM4ENPC1 | |
| SCHEMBL26297059 | 0.81 | HRH3 (0.54) | MAPTGAAME2ME1ME3 | |
| SCHEMBL16026436 | 0.79 | NCF1 (0.57) | MAPTGAANCF1ME2ME1 | |
| SCHEMBL28705770 | 0.79 | ALDH1A1 (0.51) | MAPTGAAME2ME1ME3 | |
| SCHEMBL20323922 | 0.77 | ALDH1A1 (0.51) | MAPTGAAME2ME1ME3 | |
| SCHEMBL27980498 | 0.75 | SMN1; SMN2 (0.68) | MAPTNCF1SMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL16043662 | 0.75 | MAPT (0.53) | MAPTGAANCF1ME2ME1 | |
| SCHEMBL21026182 | 0.75 | ME2 (0.49) | MAPTGAAME2ME1ME3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4395549-A1 | COMPOSITIONS AND METHODS FOR TARGETED DEGRADATION OF PROTEINS IN A PLANT CELL | Oerth Bio LLC (US) | 2024-07-10 | — | — | EP | disclosed |
| WO-2023034411-A1 | COMPOSITIONS AND METHODS FOR TARGETED DEGRADATION OF PROTEINS IN A PLANT CELL | OERTH BIO LLC (US) | 2023-03-09 | — | — | WO | disclosed |