Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.66 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.66 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.66 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.66 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.66 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.66 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.66 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.66 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.66 |
| ▸ | GSK3B | P49841 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | CES2 | O00748 | 1/20 | 0.59 |
| ▸ | CES1 | P23141 | 1/20 | 0.59 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 5/20 | 0.57 |
| ▸ | CA2 | P00918 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9118933 | 0.84 | MAPT (0.66) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL153386 | 0.83 | ALDH1A1 (0.76) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL16552644 | 0.83 | MMP1 (0.76) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL505810 | 0.81 | HDAC3 (0.68) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL1267569 | 0.81 | HDAC3 (0.68) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL459470 | 0.81 | KMT2A (0.70) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Ethylene SCHEMBL27986944 | 0.80 | HDAC3 (0.61) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL31119870 | 0.80 | HDAC3 (0.61) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL182867 | 0.79 | HDAC3 (0.66) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL5806919 | 0.79 | HDAC3 (0.66) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117603202-A | Synthesis method of pyrrolidine derivative substituted by 2-nitrogen heterocycle | 浙江工业大学 | 2024-02-27 | — | — | CN | claimed |
| CN-117603202-A | Synthesis method of pyrrolidine derivative substituted by 2-nitrogen heterocycle | 浙江工业大学 | 2024-02-27 | — | — | CN | disclosed |
| US-11465960-B2 | Labile esters of agrochemicals for controlled release and reduction of off-site movement | MONSANTO TECHNOLOGY LLC (US) | 2022-10-11 | — | — | US | disclosed |
| US-20200392063-A1 | LABILE ESTERS OF AGROCHEMICALS FOR CONTROLLED RELEASE AND REDUCTION OF OFF-SITE MOVEMENT | MONSANTO TECHNOLOGY LLC (US) | 2020-12-17 | — | — | US | disclosed |
| US-10793503-B2 | Labile esters of agrochemicals for controlled release and reduction of off-site movement | MONSANTO TECHNOLOGY LLC (US) | 2020-10-06 | — | — | US | disclosed |
| US-20180258025-A1 | LABILE ESTERS OF AGROCHEMICALS FOR CONTROLLED RELEASE AND REDUCTION OF OFF-SITE MOVEMENT | MONSANTO TECHNOLOGY LLC (US) | 2018-09-13 | — | — | US | disclosed |
| CN-104271132-B | Anticancer compounds targeting Ral gtpase and methods of using the same | 科罗拉多大学董事会法人团体 | 2018-01-12 | — | — | CN | disclosed |
| US-20170029355-A1 | LABILE ESTERS OF AGROCHEMICALS FOR CONTROLLED RELEASE AND REDUCTION OF OFF-SITE MOVEMENT | MONSANTO TECHNOLOGY LLC | 2017-02-02 | — | — | US | disclosed |
| US-9402396-B2 | Labile esters of agrochemicals for controlled release and reduction of off-site movement | MONSANTO TECHNOLOGY LLC (US) | 2016-08-02 | — | — | US | disclosed |
| CN-104557738-A | Green synthesis method of 4(3H)-quinazolinone | UNIV HUNAN | 2015-04-29 | — | — | CN | disclosed |
| CN-1391562-A | Quinazoline derivatives as medicaments | ASTRAZENECA AB (SE) | 2003-01-15 | — | — | CN | disclosed |
| CN-1384100-A | Benzo-1,3-dioxole and benzofuran substituted pentazane derivative | ABBOTT CO (US) | 2002-12-11 | — | — | CN | disclosed |
| CN-1091768-C | Novel benzo-1, 3-dioxolyl-and benzofuranyl-substituted pyrrolidine derivatives as endothelin antagonists | ABBOTT LAB CO (US) | 2002-10-02 | — | — | CN | disclosed |
| CN-1219172-A | Novel benzo-1, 3-dioxolyl-and benzofuranyl-substituted pyrrolidine derivatives as endothelin antagonists | ABBOTT LAB CO (US) | 1999-06-09 | — | — | CN | disclosed |
| US-4487772-A | CARDIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO. LTD. (JP) | 1984-12-11 | — | — | US | disclosed |
| US-4472403-A | Quinoline derivatives and pharmaceutical compositions and methods for treating cardiovascular disease with such compounds | A.C.F. CHEMIEFARMA N.V. (NL) | 1984-09-18 | — | — | US | disclosed |
| US-4468402-A | Carbostyril derivatives, process for producing the same and cardiotonic compositions containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4454130-A | CARDIOTONIC, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-12 | — | — | US | disclosed |
| EP-0030044-A1 | Quinoline derivatives, processes for their preparation, their use, pharmaceutical compositions containing them and a method for the preparation of these pharmaceutical compositions | ACF CHEMIEFARMA NV (NL) | 1981-06-10 | — | — | EP | disclosed |
| US-3932423-A | TREATMENT OF PSYCHOLOGICAL DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES (JA) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11465960-B2 | Labile esters of agrochemicals for controlled release and reduction of off-site movement | APEH, GUSB, CES2 | HDAC3 741/4885HDAC4 1004/4885HDAC1 1021/4885 |
| US-20200392063-A1 | LABILE ESTERS OF AGROCHEMICALS FOR CONTROLLED RELEASE AND REDUCTION OF OFF-SITE MOVEMENT | APEH, GUSB, CES2 | HDAC3 741/4885HDAC4 1004/4885HDAC1 1021/4885 |
| US-20170029355-A1 | LABILE ESTERS OF AGROCHEMICALS FOR CONTROLLED RELEASE AND REDUCTION OF OFF-SITE MOVEMENT | APEH, GUSB, CES2 | HDAC3 741/4885HDAC4 1004/4885HDAC1 1021/4885 |
| US-10793503-B2 | Labile esters of agrochemicals for controlled release and reduction of off-site movement | APEH, GUSB, CES2 | HDAC3 741/4885HDAC4 1004/4885HDAC1 1021/4885 |
| US-20180258025-A1 | LABILE ESTERS OF AGROCHEMICALS FOR CONTROLLED RELEASE AND REDUCTION OF OFF-SITE MOVEMENT | APEH, GUSB, CES2 | HDAC3 741/4885HDAC4 1004/4885HDAC1 1021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.