Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 8/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 5/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.33 |
| ▸ | TMPRSS15 | P98073 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4330469 | 0.96 | FABP4 (0.39) | FABP4FABP5CA2ERAP1ALDH1A1 | |
| SCHEMBL7347312 | 0.94 | FABP4 (0.38) | FABP4FABP5CA2ERAP1ALDH1A1 | |
| SCHEMBL2722431 | 0.91 | CA2 (0.39) | FABP4FABP5CA2ALDH1A1PRSS1 | |
| SCHEMBL9947946 | 0.78 | CA2 (0.34) | CA2ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL16409213 | 0.76 | CTSL (0.34) | CA2ALDH1A1SMN1; SMN2CTSS | |
| SCHEMBL23794142 | 0.73 | ALDH1A1 (0.36) | FABP4FABP5ERAP1ALDH1A1CYP1A2 | |
| SCHEMBL30471330 | 0.72 | DGAT1 (0.38) | CA2ALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL19388569 | 0.72 | CTSS (0.33) | CA2CTSS | |
| SCHEMBL16391617 | 0.72 | EPHX1 (0.36) | CA2ALDH1A1POLBSMN1; SMN2CTSS | |
| SCHEMBL9613093 | 0.71 | FFAR3 (0.40) | FABP4FABP5ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4387980-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. (US) | 2024-06-26 | — | — | EP | disclosed |
| WO-2023023631-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. (US) | 2023-02-23 | — | — | WO | disclosed |