Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.48 |
| ▸ | LIPE | Q05469 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | F10 | P00742 | 2/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.46 |
| ▸ | F7 | P08709 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8886562 | 1.00 | HPGD (0.49) | HPGDRAB9ANPC1SMN1; SMN2MAPK1 | |
| SCHEMBL3565827 | 0.92 | SMPD1 (0.54) | HPGDRAB9ANPC1SMN1; SMN2MAPK1 | |
| SCHEMBL682767 | 0.87 | MAPT (0.49) | HPGDRAB9ANPC1SMN1; SMN2MAPK1 | |
| SCHEMBL16785955 | 0.86 | GLRA1 (0.47) | HPGDRAB9ANPC1SMN1; SMN2MAPK1 | |
| SCHEMBL28815272 | 0.85 | CCR5 (0.49) | HPGDRAB9ANPC1SMN1; SMN2MAPK1 | |
| SCHEMBL28900111 | 0.85 | KDM4E (0.45) | HPGDRAB9ANPC1SMN1; SMN2MAPK1 | |
| SCHEMBL8886459 | 0.84 | MAPT (0.46) | HPGDRAB9ANPC1SMN1; SMN2MAPK1 | |
| SCHEMBL21462514 | 0.84 | POLB (0.45) | HPGDRAB9ANPC1SMN1; SMN2MAPK1 | |
| SCHEMBL10710291 | 0.84 | CFD (0.49) | HPGDRAB9ANPC1SMN1; SMN2MAPK1 | |
| SCHEMBL18869045 | 0.83 | KEAP1 (0.50) | HPGDRAB9ANPC1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116444569-A | Triphenylhydroxytyrosol and synthesis method thereof and application of triphenylhydroxytyrosol in preparation of medicines for improving aortic endothelial cell functions | 西安交通大学 | 2023-07-18 | — | — | CN | disclosed |
| CN-115850334-A | Triphenylphosphonium-hydroxytyrosol, synthesis method thereof and application thereof in preparing drugs for inhibiting cancer cell proliferation | 西安交通大学 | 2023-03-28 | — | — | CN | disclosed |