Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.46 |
| ▸ | LIPE | Q05469 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | F7 | P08709 | 1/20 | 0.45 |
| ▸ | F3 | P13726 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17833745 | 0.92 | SMPD1 (0.53) | MAPK1RAB9AALDH1A1KDM4ELMNA | |
| SCHEMBL12738664 | 0.92 | NPC1 (0.55) | MAPTRAB9AALDH1A1KDM4EF2 | |
| SCHEMBL28815272 | 0.88 | CCR5 (0.49) | MAPTMAPK1TDP1L3MBTL1C5AR1 | |
| SCHEMBL30280437 | 0.87 | HPGD (0.49) | MAPTMAPK1TDP1L3MBTL1C5AR1 | |
| SCHEMBL8886459 | 0.87 | MAPT (0.46) | MAPTMAPK1TDP1L3MBTL1C5AR1 | |
| SCHEMBL12889910 | 0.87 | GLRA1 (0.50) | MAPTMAPK1TDP1L3MBTL1CCR5 | |
| SCHEMBL14200042 | 0.87 | KEAP1 (0.53) | MAPTMAPK1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL8886562 | 0.87 | HPGD (0.49) | MAPTMAPK1TDP1L3MBTL1C5AR1 | |
| SCHEMBL12868786 | 0.87 | FFAR4 (0.54) | MAPTMAPK1TDP1L3MBTL1CCR5 | |
| SCHEMBL10710291 | 0.87 | CFD (0.49) | MAPTMAPK1TDP1L3MBTL1C5AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022270478-A1 | ANTIVIRAL AGENT | 国立大学法人北海道大学 | 2022-12-29 | — | — | WO | disclosed |
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | BRAINCELLS INC. (US) | 2011-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | NGF, DCX, BDNF | MAPT 1368/4885MAPK1 470/4885TDP1 2972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.