Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.36 |
| ▸ | POLQ | O75417 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30280786 | 0.81 | ACMSD (0.58) | ACMSDHDAC1HDAC2HDAC3KDM4E | |
| SCHEMBL27512856 | 0.80 | ACMSD (0.45) | ACMSDHDAC1HDAC2HDAC3KDM4E | |
| SCHEMBL27545241 | 0.78 | ACMSD (0.53) | ACMSDHDAC1HDAC2HDAC3KDM4E | |
| SCHEMBL27718282 | 0.76 | ACMSD (0.64) | ACMSDHDAC1HDAC2KDM4EALDH1A1 | |
| SCHEMBL3985016 | 0.76 | ACMSD (0.51) | ACMSDHDAC1HDAC2HDAC3KDM4E | |
| SCHEMBL30280751 | 0.76 | ALDH1A1 (0.55) | ACMSDHDAC1HDAC2HDAC3KDM4E | |
| SCHEMBL26800328 | 0.72 | KDM4E (0.54) | ACMSDHDAC1HDAC2KDM4EALDH1A1 | |
| SCHEMBL27636958 | 0.71 | ACMSD (0.47) | ACMSDHDAC1HDAC2HDAC3KDM4E | |
| SCHEMBL29653784 | 0.70 | BACE1 (0.44) | ACMSDHDAC1HDAC2HDAC3ALDH1A1 | |
| SCHEMBL9108966 | 0.70 | BACE1 (0.44) | ACMSDHDAC1HDAC2HDAC3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085233-A1 | NOVEL DERIVATIVES OF QUINOLINONES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-04-24 | — | — | WO | disclosed |