SCHEMBL3028133

SCHEMBL3028133

CC(=O)CC(C)=O.c1cc2cc-2c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMO O15229 1/20 0.45
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
ESR1 P03372 1/20 0.42
MGLL Q99685 1/20 0.42
AOC3 Q16853 3/20 0.42
ERCC5 P28715 1/20 0.41
FEN1 P39748 1/20 0.41
APP P05067 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
CYP2C19 P33261 2/20 0.40
KDM4E B2RXH2 2/20 0.40
HDAC1 Q13547 2/20 0.40
ALDH1A1 P00352 1/20 0.40
CYP1A2 P05177 1/20 0.40
HIF1A Q16665 1/20 0.40
APOBEC3A P31941 1/20 0.40
GFER P55789 1/20 0.40
APOBEC3G Q9HC16 1/20 0.40
BCL2 P10415 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9566050 0.98 KMO (0.43) KMOMEN1KMT2AESR1MGLL
Butanone SCHEMBL27536691 0.85 ALDH1A1 (0.50) KMOMEN1KMT2AESR1APP
Acetone SCHEMBL18784619 0.84 KMO (0.52) KMOMEN1KMT2AESR1MGLL
Biphenyl SCHEMBL27660096 0.82 MAPT (0.56) ERCC5FEN1KDM4EHDAC1ALDH1A1
Benzene SCHEMBL28772928 0.81 KMO (0.56) KMOMEN1KMT2AESR1MGLL
Acetic Acid SCHEMBL734741 0.81 KMO (0.56) KMOMEN1KMT2AESR1MGLL
Acetic Acid Methyl Ester SCHEMBL5167069 0.80 ALDH1A1 (0.50) KMOMEN1KMT2AESR1MGLL
Acetamide SCHEMBL1259199 0.79 DHODH (0.48) KMOMEN1KMT2AESR1APP
Pyruvate SCHEMBL27990027 0.77 KMO (0.52) KMOMEN1KMT2AESR1MGLL
SCHEMBL8719391 0.76 ALDH1A1 (0.39) MEN1KMT2ACYP2C19KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112795829-B Fine-grain hard alloy and preparation method thereof 广东正信硬质材料技术研发有限公司 2022-03-15 CN claimed
CN-112795829-A Fine-grain hard alloy and preparation method thereof 广东正信硬质材料技术研发有限公司 2021-05-14 CN claimed
CN-107382688-A Efficiently synthesize the method and its application of tri acetylacetonato ruthenium 郴州高鑫铂业有限公司 2017-11-24 CN claimed
EP-1293502-B1 Process for the preparation of (meth)acrylates of alkylimidazolidone ARKEMA FRANCE (FR) 2007-05-09 EP claimed
US-20040147761-A1 Process for preparation of alkylimidazolidone (meth)acrylates ATOFINA (FR) 2004-07-29 US claimed
US-6706887-B2 REACTING (METH)ACRYLATE COMPOUND WITH WITH A HETEROCYCLIC ALCOHOL IN PRESENCE OF A CATALYST COMPRISING CHELATE COMPOUND FORMED OF LITHIUM AND OF A 1,3-DICARBONYL COMPOUD ATOFINA (FR) 2004-03-16 US claimed
US-20030096931-A1 Process for the preparation of alkylimidazolidone (meth)acrylates ATOFINA (FR) 2003-05-22 US claimed
EP-1293502-A1 Process for the preparation of (meth)acrylates of alkylimidazolidone Atofina (FR) 2003-03-19 EP claimed
EP-0619309-B1 Process for the preparation of alkylimidazolidone (meth)acrylates ATOCHEM ELF SA (FR) 2000-07-12 EP claimed
EP-0712846-B1 Process of preparation of alkylimidazolidone methacrylates ATOCHEM ELF SA (FR) 1999-08-11 EP claimed
US-5610313-A Process for the preparation of alkylimidazolidone (meth) acrylates ELF ATOCHEM S.A. (FR) 1997-03-11 US claimed
EP-0712846-A1 Process of preparation of alkylimidazolidone methacrylates ELF ATOCHEM S.A. (FR) 1996-05-22 EP claimed
EP-0619309-A1 Process for the preparation of alkylimidazolidone (meth)acrylates ELF ATOCHEM S.A. (FR) 1994-10-12 EP claimed
US-4900730-A USING CHELATING AGENT AND SOLVENT; HIGH OSMOTIC PRESSURE TOYO JOZO CO., LTD. (JP) 1990-02-13 US claimed
US-4202990-A ESTER INTERCHANGE USING ZIRCONIUM OR CALCIUM CHELATES AS CATALYSTS MITSUBISHI RAYON COMPANY, LIMITED (JP) 1980-05-13 US claimed
CN-115698177-A Heat-curable composition and cured product thereof 株式会社钟化 2023-02-03 CN disclosed
CN-112795829-B Fine-grain hard alloy and preparation method thereof 广东正信硬质材料技术研发有限公司 2022-03-15 CN disclosed
US-4900730-A USING CHELATING AGENT AND SOLVENT; HIGH OSMOTIC PRESSURE TOYO JOZO CO., LTD. (JP) 1990-02-13 US disclosed
US-4553972-A FLEXIBLE POLYMER, CHELATION SYNTEX (U.S.A.) INC. (US) 1985-11-19 US disclosed
US-4097461-A Oxidative coupling of alkylphenols or 1-naphthols catalyzed by metal complexes of diketo compounds ICI AMERICAS INC. (US) 1978-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040147761-A1 Process for preparation of alkylimidazolidone (meth)acrylates ILK, LAMTOR3, MNAT1 KMO 3187/4885MEN1 1818/4885KMT2A 134/4885
US-20030096931-A1 Process for the preparation of alkylimidazolidone (meth)acrylates ILK, ADH1A, MNAT1 KMO 2765/4885MEN1 1641/4885KMT2A 118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.